Poly-L-proline
Poly-L-proline (CAS: 25191-13-3), with the empirical formula C5H9NO2 and a molecular weight of 115.13 g/mol, is a synthetic homopolymer of the amino acid L-proline. This polypeptide is known for its unique helical structure, particularly its stable polyproline II conformation. It is a valuable tool in biochemical research, often employed in studies related to protein folding, peptide conformation, and as a model system for specific secondary structures. Stored at -20°C.

Biochemical Research
Poly-L-proline serves as a model compound in structural biology research. Its well-defined helical structure aids in understanding protein folding mechanisms and the stability of peptide secondary structures.
Peptide Conformation Studies
It is used to investigate the conformational properties of proline-rich peptides. The stable polyproline II helix is critical for understanding molecular recognition and protein-protein interactions.
Material Science Applications
Research into the physical and chemical properties of polyamino acids can lead to novel biomaterials. Poly-L-proline's specific structural characteristics are explored for potential applications in biomimetic materials.
| Molecular weight | 115.13 |
|---|---|
| Empirical formula | C5H9NO2 |
| Storage temperature | −20°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Mol Wt | mol wt >30,000 |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Poly-L-proline used for?
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Poly-L-proline is primarily used in biochemical and structural biology research as a model compound to study peptide conformation, protein folding, and the stability of the polyproline II helical structure.
What is the CAS number and formula for Poly-L-proline?
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The CAS number for Poly-L-proline is 25191-13-3, and its empirical formula is C5H9NO2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Poly-L-proline with a molecular weight greater than 30,000. We do not represent this product as USP, BP, or EP grade; it is suitable for research and technical applications.
What are the safety and handling requirements for Poly-L-proline?
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Handling Poly-L-proline requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. The product has a WGK rating of 3 in Germany, indicating a high hazard to water.
How is Poly-L-proline packed, shipped, and exported?
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Poly-L-proline is typically stored at -20°C. Tech Serve Solutions ensures secure and compliant packaging for international shipment and export, adhering to all relevant regulations for chemical handling and transport.
How can I request a sample or quote for Poly-L-proline?
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To request a sample or a quote for Poly-L-proline, please contact our sales department through the website or by phone, providing your specific requirements and shipping details.
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