N-Boc-piperidine-3-methanol
N-Boc-piperidine-3-methanol (CAS: 116574-71-1), a valuable heterocyclic building block with the molecular formula C11H21NO3 and a molecular weight of 215.29 g/mol, is supplied by TSS. This compound serves as a key intermediate in the synthesis of various biologically active molecules. Its protected piperidine structure makes it particularly useful in medicinal chemistry research and development for creating novel therapeutic agents.
- IUPAC
- 1,1-Dimethylethyl 3-(hydroxymethyl)-1-piperidinecarboxylate,3-(Hydroxymethyl)-N-(tert-butoxycarbonyl)piperidine,N-Boc-3-(hydroxymethyl)piperidine
- Synonyms
- 1,1-Dimethylethyl 3-(hydroxymethyl)-1-piperidinecarboxylate3-(Hydroxymethyl)-N-(tert-butoxycarbonyl)piperidineN-Boc-3-(hydroxymethyl)piperidine

Synthesis of Pim-1 Inhibitors
N-Boc-piperidine-3-methanol is utilised as a reactant in the synthetic pathways leading to potent Pim-1 inhibitors, which are investigated for various therapeutic applications.
Development of Vasopressin Receptor Antagonists
This building block facilitates the synthesis of vasopressin 1b receptor antagonists, compounds explored for their potential in treating conditions related to vasopressin activity.
CXCR4 Antagonists for Anti-HIV Agents
It serves as a precursor in the creation of CXCR4 antagonists, which are being developed as potential anti-HIV therapeutic agents due to their role in viral entry inhibition.
Amide CCR5 Antagonist Synthesis
The compound is employed in the chemical synthesis of amide CCR5 antagonists, contributing to the development of novel modulators for the CCR5 receptor.
Inhibitors of Multidrug Efflux Pumps
N-Boc-piperidine-3-methanol is a building block for PSSRI-based inhibitors designed to counteract multidrug efflux pumps in S. aureus.
Human GnRH Receptor Antagonists
This intermediate is a component in the synthetic routes towards human GnRH receptor antagonists, researched for their potential endocrinological applications.
| Molecular weight | 215.29 |
|---|---|
| Empirical formula | C11H21NO3 |
| Assay | 97% |
| Application | Reactant for synthesis of:• Pim-1 inhibitors1• Vasopressin1b receptor antagonists2• CXCR4 antagonists as anti-HIV agents3• Amide CCR5 antagonist4• PSSRI-based inhibitors of S. aureus multidrug efflux pumps5• Human GnRH receptor antagonists6 |
| Melting point | 77-81 °C |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is N-Boc-piperidine-3-methanol used for?
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N-Boc-piperidine-3-methanol (CAS: 116574-71-1) is primarily used as a reactant and building block in the synthesis of various biologically active compounds, including Pim-1 inhibitors, vasopressin receptor antagonists, CXCR4 antagonists, amide CCR5 antagonists, inhibitors of S. aureus multidrug efflux pumps, and human GnRH receptor antagonists.
What is the CAS number and molecular formula for N-Boc-piperidine-3-methanol?
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The CAS number for N-Boc-piperidine-3-methanol is 116574-71-1, and its molecular formula is C11H21NO3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies N-Boc-piperidine-3-methanol with an assay of 97%. This product is supplied for research and chemical synthesis purposes and is not represented as USP, BP, EP, or any other pharmacopoeia grade.
What are the safety considerations for handling N-Boc-piperidine-3-methanol?
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N-Boc-piperidine-3-methanol has a WGK (German water hazard class) of 3, indicating it is a substance with high hazard to water. Appropriate personal protective equipment should be worn, and it should be handled in a well-ventilated area to avoid exposure.
How is N-Boc-piperidine-3-methanol packed, shipped, and exported?
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N-Boc-piperidine-3-methanol is carefully packed according to industry standards to ensure safe transit. TSS is an experienced global supplier and exporter, adhering to all necessary regulations for international chemical shipments.
How can I request a sample or quote for N-Boc-piperidine-3-methanol?
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To request a sample or a quotation for N-Boc-piperidine-3-methanol, please contact the TSS sales team through the website or by phone, providing your specific requirements and shipping details.
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