N-Boc-pyrrolidine
N-Boc-pyrrolidine (CAS: 86953-79-9), a pyrrolidine derivative with the molecular formula C9H17NO2 and a molecular weight of 171.24 g/mol, serves as a valuable building block in organic synthesis. Its tert-butoxycarbonyl (Boc) protecting group facilitates selective reactions. This compound is primarily employed in chemical synthesis, particularly for constructing more complex heterocyclic molecules and pharmaceutical intermediates. It is supplied by TSS with an assay of 97%.
- IUPAC
- tert-Butyl 1-pyrrolidinecarboxylate
- Synonyms
- tert-Butyl 1-pyrrolidinecarboxylate
Organic Synthesis
N-Boc-pyrrolidine is a versatile intermediate in multi-step organic synthesis. The Boc group offers protection to the pyrrolidine nitrogen, allowing for controlled functionalization at other positions of the molecule or during subsequent reaction steps.
Pharmaceutical Intermediate Development
Its structure makes it a useful synthon for the preparation of biologically active compounds and advanced pharmaceutical intermediates. The pyrrolidine ring is a common motif found in many drug molecules.
Heterocyclic Chemistry
As a functionalized pyrrolidine, it is frequently utilized in the synthesis of diverse heterocyclic compounds, expanding the scope of chemical libraries for drug discovery and material science.
| Molecular weight | 171.24 |
|---|---|
| Empirical formula | C9H17NO2 |
| Assay | 97% |
| Boiling point | 80 °C/0.2 mmHg(lit.) |
| Density | 0.977 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.449(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 86 °C / 186.8 °F |
| Transport (UN / ADR) | NA 1993 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is N-Boc-pyrrolidine used for?
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N-Boc-pyrrolidine is used as a building block in organic synthesis, particularly for creating complex heterocyclic molecules and pharmaceutical intermediates. The tert-butoxycarbonyl (Boc) group acts as a protecting group for the nitrogen atom.
What is the CAS number and formula for N-Boc-pyrrolidine?
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The CAS number for N-Boc-pyrrolidine is 86953-79-9, and its empirical formula is C9H17NO2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies N-Boc-pyrrolidine with a purity of 97%. This product is not represented as USP, BP, EP, or any other pharmacopoeia grade.
How should N-Boc-pyrrolidine be handled?
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N-Boc-pyrrolidine is classified with Warning as a GHS07 symbol, with hazard statements H315 (Causes skin irritation), H319 (Causes serious eye irritation), and H335 (May cause respiratory irritation). Appropriate personal protective equipment, including eyeshields, gloves, and respiratory protection (such as a multi-purpose combination respirator cartridge or ABEK type filter), should be used. Handle in a well-ventilated area.
How is N-Boc-pyrrolidine shipped?
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N-Boc-pyrrolidine is shipped according to regulations, classified under NA 1993, Packing Group III. TSS is a global supplier and exporter of chemicals.
How can I request a sample or quote for N-Boc-pyrrolidine?
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To request a sample or quote for N-Boc-pyrrolidine, please use the contact form on the Tech Serve Solutions website or contact our sales department directly.
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