N-Boc-piperidine
N-Boc-piperidine (CAS 75844-69-8), with the molecular formula C10H19NO2 and a molecular weight of 185.26 g/mol, is a key heterocyclic building block. This compound serves as a valuable substrate in organic synthesis, particularly in procedures such as two-step alpha-arylation reactions. It is widely employed in chemical synthesis for the construction of complex molecular architectures.
- IUPAC
- 1-Boc-piperidine,N-(tert-Butoxycarbonyl)piperidine,N-Boc-tetrahydropyridine
- Synonyms
- 1-Boc-piperidineN-(tert-Butoxycarbonyl)piperidineN-Boc-tetrahydropyridine
Organic Synthesis Intermediate
N-Boc-piperidine is utilized as a substrate in multi-step organic synthesis. Its protected piperidine structure makes it ideal for introducing piperidine moieties into larger molecules.
Alpha-Arylation Reactions
This compound serves as a substrate in a two-step alpha-arylation procedure, facilitating the formation of carbon-carbon bonds at the alpha position of the piperidine ring.
Heterocyclic Chemistry
As a derivative of piperidine, N-Boc-piperidine is fundamental in heterocyclic chemistry research and development, enabling the synthesis of diverse nitrogen-containing compounds.
| Molecular weight | 185.26 |
|---|---|
| Empirical formula | C10H19NO2 |
| Assay | 98% |
| Density | 0.964 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.454(lit.) |
| Application | Substrate used in a two-step α-arylation procedure.7 |
Hazard statements
- H301Toxic if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
- H400Very toxic to aquatic life
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P273Avoid release to the environment
- P301IF SWALLOWED
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 86 °C / 186.8 °F |
| Transport (UN / ADR) | UN 2810 6.1/PG 3 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T,N |
| Risk statements (R) | 25-36/37/38-50 |
| Safety statements (S) | 26-36-45-60-61 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is N-Boc-piperidine used for?
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N-Boc-piperidine is primarily used as a substrate in organic synthesis, particularly in alpha-arylation procedures and as a building block in heterocyclic chemistry.
What is the CAS number and molecular formula for N-Boc-piperidine?
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The CAS number for N-Boc-piperidine is 75844-69-8, and its molecular formula is C10H19NO2.
What grade and purity does Tech Serve Solutions supply for N-Boc-piperidine?
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Tech Serve Solutions supplies N-Boc-piperidine with an assay of 98%. We do not represent this product as USP, BP, or EP grade.
What are the primary safety hazards associated with N-Boc-piperidine?
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N-Boc-piperidine is classified as Dangerous (GHS06, GHS09), with signal words indicating Danger. It is toxic if swallowed (H301), causes skin irritation (H315), causes serious eye irritation (H319), may cause respiratory irritation (H335), and is very toxic to aquatic life (H400). Appropriate personal protective equipment, including eyeshields and gloves, is essential when handling.
Is N-Boc-piperidine a controlled substance?
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The provided data does not indicate that N-Boc-piperidine is a controlled substance.
How is N-Boc-piperidine packed, shipped, and exported?
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Tech Serve Solutions specialises in global supply and export of fine chemicals, including N-Boc-piperidine, adhering to all necessary shipping regulations for hazardous materials like UN 2810 (6.1/PG 3).
How can I request a sample or quote for N-Boc-piperidine?
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Please contact our sales team through the website to request a sample or a formal quotation for N-Boc-piperidine.
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