N-Boc-hexamethyleneimine
N-Boc-hexamethyleneimine (CAS: 123387-52-0), with the molecular formula C11H21NO2 and a molecular weight of 199.29 g/mol, is a key heterocyclic building block. This compound serves as a versatile intermediate in organic synthesis, particularly for introducing the hexamethyleneimine (azepane) moiety into more complex molecular structures. Its tert-butoxycarbonyl (Boc) protecting group facilitates controlled reactions and selective deprotection in multi-step synthetic pathways.
- IUPAC
- 1-(tert-Butoxycarbonyl)hexahydroazepine,1-Boc-perhydroazepine,1-Boc-azepane,1-Boc-hexahydro-1H-azepine,1-Boc-homopiperidine,N-Boc-azepane,N-Boc-perhydroazepine,Hexahydro-1H-azepine-1-carboxylic acid 1,1-dimethylethyl ester
- Synonyms
- 1-(tert-Butoxycarbonyl)hexahydroazepine1-Boc-perhydroazepine1-Boc-azepane1-Boc-hexahydro-1H-azepine1-Boc-homopiperidineN-Boc-azepaneN-Boc-perhydroazepineHexahydro-1H-azepine-1-carboxylic acid 1,1-dimethylethyl ester
Organic Synthesis Intermediate
N-Boc-hexamethyleneimine is widely employed as a protected amine building block in the synthesis of complex organic molecules. The Boc group allows for regioselective functionalization of the azepane ring.
Pharmaceutical Intermediate
This compound is valuable in the development of novel pharmaceutical agents. Its structure can be incorporated into drug candidates targeting various therapeutic areas.
Heterocyclic Chemistry
As a derivative of azepane, it is utilized in the study and synthesis of nitrogen-containing heterocyclic compounds, which are prevalent in many biologically active molecules.
| Molecular weight | 199.29 |
|---|---|
| Empirical formula | C11H21NO2 |
| Assay | 97% |
| Density | 0.967 g/mL at 25 °C |
| Refractive index | n20/D 1.457 |
| Storage temperature | −20°C |
Hazard statements
- H301Toxic if swallowed
- H319Causes serious eye irritation
- H400Very toxic to aquatic life
Precautionary statements
- P273Avoid release to the environment
- P301IF SWALLOWED
- P305IF IN EYES
| Flash point | 105 °C / 221 °F |
|---|---|
| Transport (UN / ADR) | UN 2810 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T,N |
| Risk statements (R) | 25-36-50 |
| Safety statements (S) | 26-45-61 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is N-Boc-hexamethyleneimine used for?
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N-Boc-hexamethyleneimine is primarily used as a protected building block in organic synthesis, particularly for introducing the hexamethyleneimine (azepane) structure into pharmaceuticals and other complex organic molecules.
What are the CAS number and molecular formula for N-Boc-hexamethyleneimine?
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The CAS number for N-Boc-hexamethyleneimine is 123387-52-0, and its molecular formula is C11H21NO2.
What grade and purity does Tech Serve Solutions supply for N-Boc-hexamethyleneimine?
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Tech Serve Solutions supplies N-Boc-hexamethyleneimine with a minimum assay of 97%. This product is intended for research and chemical synthesis purposes and is not represented as USP, BP, EP, or any other pharmacopoeia grade.
How should N-Boc-hexamethyleneimine be handled safely?
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N-Boc-hexamethyleneimine is classified as Danger. It is toxic if swallowed (H301), causes serious eye irritation (H319), and is very toxic to aquatic life (H400). Handle with appropriate personal protective equipment in a well-ventilated area, avoid release to the environment, and consult the Safety Data Sheet for detailed handling procedures.
How is N-Boc-hexamethyleneimine packed, shipped, and exported?
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N-Boc-hexamethyleneimine is packed according to safety regulations for hazardous materials. It is shipped internationally by Tech Serve Solutions, a specialist global supplier, adhering to all relevant transport guidelines for chemicals classified under UN 2810, Class 6.1, Packing Group III.
How can I request a quote or sample for N-Boc-hexamethyleneimine?
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To request a quote or a sample of N-Boc-hexamethyleneimine, please contact the Tech Serve Solutions sales team through our website or by calling us directly.
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