Methyl-6-bromopyridine-2-carboxylate
Methyl-6-bromopyridine-2-carboxylate (CAS 26218-75-7) is a halogenated pyridine building block with the molecular formula C7H6BrNO2 and a molar mass of 216.03 g/mol. Supplied as a solid (melting point 92-96 °C) at 97% assay, it pairs a reactive ring bromide with a methyl ester, making it a versatile intermediate in pharmaceutical and fine-chemical synthesis. Tech Serve Solutions supplies and exports this reagent-grade heterocyclic building block worldwide.
- IUPAC
- Methyl 6-bromo-2-pyridinecarboxylate,Methyl 6-bromopicolinate
- Synonyms
- Methyl-6-bromopyridine-2-carboxylateMethyl 6-bromo-2-pyridinecarboxylateMethyl 6-bromopicolinateMethyl 6-bromopyridine-2-carboxylate6-bromopyridine-2-carboxylic acid methyl esterCAS 26218-75-7
Pyridine building block for synthesis
Serves as a halogenated heterocyclic building block in multi-step organic synthesis. The 6-bromo substituent on the pyridine ring is a convenient site for further functionalisation.
Cross-coupling intermediate
The aryl bromide is well suited to palladium-catalysed cross-coupling chemistry, such as Suzuki, Stille and related reactions, enabling the construction of substituted bipyridines and biaryl systems.
Pharmaceutical intermediate
Used as an intermediate in the preparation of pyridine-containing pharmaceutical candidates and active pharmaceutical ingredients, where the pyridine carboxylate scaffold is a common motif.
Ester for further derivatisation
The methyl ester can be hydrolysed, reduced or converted to amides and other derivatives, providing a handle for elaborating the picolinate core into more complex targets.
Laboratory and research reagent
Applied as a research-grade reagent in medicinal chemistry, ligand synthesis and academic discovery programmes that rely on functionalised pyridine scaffolds.
| Molecular weight | 216.03 |
|---|---|
| Empirical formula | C7H6BrNO2 |
| Assay | 97% |
| Melting point | 92-96 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H318Causes serious eye damage
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 37/38-41 |
| Safety statements (S) | 26-39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Methyl-6-bromopyridine-2-carboxylate used for?
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It is used mainly as a halogenated pyridine building block and intermediate in organic and pharmaceutical synthesis. The reactive 6-bromo position supports palladium-catalysed cross-coupling reactions, while the methyl ester offers a further point for derivatisation into amides, acids, alcohols and related structures.
What is the CAS number and molecular formula of Methyl-6-bromopyridine-2-carboxylate?
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The CAS number is 26218-75-7 and the molecular formula is C7H6BrNO2, with a molecular weight of 216.03 g/mol. The MDL number is MFCD06203934 and the PubChem Substance ID is 24883731.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product at a typical assay of 97% as a reagent/research-grade material; it is a solid with a melting point of 92-96 °C (literature). We do not represent it as USP, BP or EP pharmacopoeia grade. A certificate of analysis can be provided with each batch on request.
What are the safety and handling requirements?
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The product is classified Danger (GHS05, GHS07) with hazard statements H315 (causes skin irritation), H318 (causes serious eye damage) and H335 (may cause respiratory irritation). Handle with gloves, eye/face protection and an N95-type dust mask, avoid dust formation, and work with adequate ventilation. It carries a German Water Hazard Class (WGK) of 3. Always consult the Safety Data Sheet before use.
How is Methyl-6-bromopyridine-2-carboxylate packed, shipped and exported?
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It is supplied in sealed laboratory and bulk packaging sized to your requirement, with appropriate labelling and documentation. Tech Serve Solutions exports worldwide and arranges shipment in line with applicable transport and dangerous-goods regulations, accompanied by an SDS and certificate of analysis.
How do I request a sample or quote?
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Contact Tech Serve Solutions with your required quantity, purity and destination, and our team will confirm availability, lead time and packaging. Samples and full commercial quantities are available to support evaluation and scale-up.
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