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Metronidazole

CAS 443-48-1C6H9N3O3Heterocyclic Building Blocks

Metronidazole (CAS 443-48-1) is a 5-nitroimidazole compound with the molecular formula C6H9N3O3 and a molar mass of 171.15 g/mol. Also known as 2-methyl-5-nitroimidazole-1-ethanol, it is a crystalline solid melting at 159-161 °C and is one of the most widely studied antiprotozoal and antibacterial agents. Tech Serve Solutions supplies it at purum grade, assay ≥98.0% (HPLC), as a reference and research-grade material for laboratory, analytical and synthesis use.

IUPAC
2-Methyl-5-nitroimidazole-1-ethanol
Synonyms
Metronidazole2-Methyl-5-nitroimidazole-1-ethanol2-(2-Methyl-5-nitro-1H-imidazol-1-yl)ethanol1-(2-Hydroxyethyl)-2-methyl-5-nitroimidazole2-Methyl-5-nitro-1H-imidazole-1-ethanol
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Metronidazole (C6H9N3O3) — chemical structure, CAS 443-48-1; Chemistry, fine chemical supplied by Tech Serve Solutions
AntibacterialAntibioticsAntibiotics A to ZAntibiotics G-MAntibiotics by ApplicationBiochemicals and ReagentsBuilding BlocksC3 to C8Chemical Structure ClassChemical Synthesis
01 /Applications

Antiprotozoal and antibacterial research

Metronidazole is a well-established 5-nitroimidazole active against anaerobic bacteria and protozoa. It is used as a reference compound in microbiology and pharmacological research investigating these organisms.

Pharmaceutical reference standard

Supplied at ≥98.0% (HPLC) purity, it serves as a characterised reference material for method development, identity confirmation and quality-control workflows.

Analytical and chromatographic use

The defined assay and melting point make it suitable as a calibration and identification standard in HPLC and related analytical techniques.

Heterocyclic building block

As a nitroimidazole bearing a hydroxyethyl side chain, it functions as a heterocyclic building block in chemical synthesis and structure-activity studies.

Biochemical and reagent applications

It is used as a biochemical reagent in laboratory studies of nitroimidazole chemistry and the mechanisms of anaerobic and protozoal systems.

02 /Properties
Molecular weight171.15
Empirical formulaC6H9N3O3
Assay≥98.0% (HPLC)
Gradepurum
Storage temperature2-8°C
Melting point159-161 °C(lit.)159-161 °C
03 /Safety & handling
GHS hazard pictogram: Health hazard (GHS08)
Health hazard
Warning

Hazard statements

  • H351Suspected of causing cancer

Precautionary statements

  • P281Use personal protective equipment as required
Protective equipmentEyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
Water hazard class (WGK, DE)3
Hazard codes (EU)Xn
Risk statements (R)40
Safety statements (S)36/37

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
443-48-1
MDL number
MFCD00009750
Beilstein registry
611683
05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is Metronidazole used for?

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Metronidazole is a 5-nitroimidazole compound widely recognised for activity against anaerobic bacteria and protozoa. In a supply and laboratory context it is used as an antibacterial and antiprotozoal reference compound, an analytical and chromatographic standard, a biochemical reagent and a heterocyclic building block for synthesis and research.

What is the CAS number and molecular formula of Metronidazole?

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Metronidazole has the CAS number 443-48-1 and the molecular formula C6H9N3O3, with a molecular weight of 171.15 g/mol. Its chemical name is 2-methyl-5-nitroimidazole-1-ethanol (EC number 207-136-1; MDL MFCD00009750; Beilstein 611683).

What grade and purity does Tech Serve Solutions supply?

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Tech Serve Solutions supplies Metronidazole at purum grade with an assay of ≥98.0% (HPLC). It is offered as a research and reference-grade material; we do not represent it as USP, BP or EP pharmacopoeia grade unless explicitly agreed and documented for a specific order.

What are the safety and handling requirements for Metronidazole?

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Metronidazole carries GHS08 with the signal word Warning and hazard statement H351 (suspected of causing cancer). Avoid exposure and obtain special instructions before use (P281). Use eye protection, gloves and appropriate respiratory protection, handle under controlled laboratory conditions, and consult the Safety Data Sheet before use. It is classified WGK 3 (high hazard to water) and must be kept out of drains and watercourses.

How should Metronidazole be stored?

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Store Metronidazole at 2-8 °C in a tightly closed container, protected from moisture and kept away from incompatible materials. Refer to the accompanying Safety Data Sheet for full storage and stability guidance.

How is Metronidazole packed, shipped and exported?

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Metronidazole is packed in sealed, labelled containers with pack sizes selected to suit laboratory, pilot and bulk requirements. As a global supplier and exporter since 1998, Tech Serve Solutions arranges compliant documentation, labelling and international dispatch, with a Safety Data Sheet provided for every consignment.

How do I request a sample or quote?

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Contact Tech Serve Solutions with your required quantity, pack size and destination, and our team will respond with availability, lead time and a formal quotation. Samples can be discussed against documented technical and end-use requirements.

Need Metronidazole in a specific grade or volume?