Methyl-1H-1,2,4-triazole-3-carboxylate
Methyl-1H-1,2,4-triazole-3-carboxylate (CAS 4928-88-5; C4H5N3O2; molar mass 127.10 g/mol) is a crystalline 1,2,4-triazole heterocyclic building block bearing a methyl ester group. It is used in research and fine-chemical synthesis as an intermediate for constructing triazole-based molecules in medicinal chemistry, agrochemical and materials programmes. Tech Serve Solutions supplies it at 98% assay (MDL MFCD00135989) for laboratory, discovery and process-development applications worldwide.
- Synonyms
- Methyl-1H-1,2,4-triazole-3-carboxylateMethyl 1H-1,2,4-triazole-3-carboxylateMethyl 1H-1,2,4-triazole-5-carboxylate1H-1,2,4-triazole-3-carboxylic acid methyl esterCAS 4928-88-5C4H5N3O2MFCD00135989
Heterocyclic building block
Serves as a versatile 1,2,4-triazole scaffold for chemical synthesis, allowing further functionalisation at the ring nitrogen and at the ester carbon. It is widely catalogued among heterocyclic building blocks and triazole intermediates.
Pharmaceutical intermediate research
Used in medicinal-chemistry and discovery programmes where the 1,2,4-triazole-carboxylate motif is incorporated into candidate molecules. The methyl ester offers a convenient handle for amidation, hydrolysis to the carboxylic acid, or other transformations.
Agrochemical synthesis
The 1,2,4-triazole core is a common feature in crop-protection chemistry, and this carboxylate ester can act as a starting material or intermediate in such synthetic routes.
Reference and analytical use
Supplied at a defined 98% assay with PubChem and MDL identifiers, it is suitable as a characterised reagent for method development and laboratory-scale studies.
| Molecular weight | 127.10 |
|---|---|
| Empirical formula | C4H5N3O2 |
| Assay | 98% |
| Melting point | 196-199 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Methyl-1H-1,2,4-triazole-3-carboxylate used for?
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It is primarily used as a heterocyclic building block and synthetic intermediate. The 1,2,4-triazole ring and its methyl ester make it useful in medicinal-chemistry, agrochemical and materials research, where the ester can be hydrolysed, amidated or otherwise elaborated into more complex triazole derivatives.
What is the CAS number and molecular formula of Methyl-1H-1,2,4-triazole-3-carboxylate?
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The CAS number is 4928-88-5 and the molecular formula is C4H5N3O2, with a molecular weight of 127.10 g/mol. Its MDL number is MFCD00135989 and its PubChem Substance ID is 24877742.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Methyl-1H-1,2,4-triazole-3-carboxylate at 98% assay as a research and technical-grade reagent. We do not represent it as a USP, BP or EP pharmacopoeia grade. A certificate of analysis can be provided with each batch on request.
What are the safety and handling requirements?
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It is classified GHS07 with signal word Warning and the hazard statements H315 (causes skin irritation), H319 (causes serious eye irritation) and H335 (may cause respiratory irritation). Handle with gloves, eye protection and an N95-type dust mask, avoid generating dust, and follow precautionary statements P261 and P305+P351+P338. It carries WGK 3 (German water-hazard class) and should be kept out of drains and watercourses. Always consult the SDS before use.
How is Methyl-1H-1,2,4-triazole-3-carboxylate packed, shipped and exported?
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It is packed as a solid in tightly sealed containers appropriate to the order size, from research quantities to bulk, and labelled in line with GHS requirements. As a global supplier since 1998, Tech Serve Solutions arranges compliant documentation and export shipping; pack sizes and Incoterms can be agreed at the time of enquiry.
How do I request a sample or quote?
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Contact Tech Serve Solutions with the quantity, required pack size and destination, and our team will respond with availability, lead time and a quotation. Samples for evaluation can be discussed alongside your enquiry.
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