N,5-Dimethoxy-N-methylnicotinamide
N,5-Dimethoxy-N-methylnicotinamide (CAS 1045855-73-9) is a substituted pyridine building block with the molecular formula C9H12N2O3 and a molar mass of 196.20 g/mol. Structurally it is the N-methoxy-N-methyl amide (Weinreb amide) of 5-methoxynicotinic acid, combining a methoxy-pyridine core with a controlled acyl-transfer group. It is used principally in pharmaceutical and fine-chemical research as a heterocyclic intermediate for organic synthesis. Tech Serve Solutions supplies and exports it as a research-grade material.
- Synonyms
- N,5-Dimethoxy-N-methylnicotinamideN,5-Dimethoxy-N-methylpyridine-3-carboxamide5-Methoxy-N-methoxy-N-methylnicotinamide5-Methoxynicotinic acid Weinreb amideCAS 1045855-73-9
Weinreb amide acylating reagent
As an N-methoxy-N-methyl amide, it serves as a controlled acyl donor that reacts cleanly with organometallic reagents to deliver the corresponding ketones, helping to avoid over-addition to tertiary alcohols.
Pyridine building block for synthesis
The 5-methoxypyridine scaffold is a useful heterocyclic building block for assembling more complex molecules, supporting further functionalisation of the ring and the pendant amide.
Pharmaceutical intermediate
It is used in medicinal-chemistry and pharmaceutical research programmes as an intermediate towards pyridine-containing target structures and analogue libraries.
Aldehyde and ketone precursor
Reduction or organometallic addition to the Weinreb amide provides convenient access to the related aldehyde or ketones, making it a practical precursor in multi-step routes.
Laboratory research and method development
The defined, single-compound nature of the material suits exploratory chemistry, reaction screening and analytical method development in research laboratories.
| Molecular weight | 196.20 |
|---|---|
| Empirical formula | C9H12N2O3 |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is N,5-Dimethoxy-N-methylnicotinamide used for?
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It is used mainly as a heterocyclic building block and Weinreb amide intermediate in pharmaceutical and fine-chemical synthesis. The N-methoxy-N-methyl amide group acts as a controlled acyl donor for preparing ketones and related carbonyl compounds from the methoxy-pyridine core.
What is the CAS number and molecular formula of N,5-Dimethoxy-N-methylnicotinamide?
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The CAS number is 1045855-73-9. Its molecular formula is C9H12N2O3 (Hill notation) with a molecular weight of 196.20 g/mol. It is the N-methoxy-N-methyl (Weinreb) amide of 5-methoxynicotinic acid.
What grade and purity does Tech Serve Solutions supply?
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It is supplied as a research/technical-grade building block for synthesis and laboratory use. A batch-specific assay is confirmed on the Certificate of Analysis accompanying each lot. We do not represent this material as USP, BP or EP pharmacopoeial grade; if you require a particular specification, please state it with your enquiry.
How should N,5-Dimethoxy-N-methylnicotinamide be handled and stored?
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Handle as a research chemical using good laboratory practice: wear suitable gloves, eye protection and a lab coat, avoid dust formation and skin or eye contact, and work with adequate ventilation. Store tightly closed in a cool, dry place away from incompatible materials. No specific GHS hazard classification was provided in our source data, so review the current Safety Data Sheet before use and follow it.
How is N,5-Dimethoxy-N-methylnicotinamide packed, shipped and exported?
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It is packed in sealed, appropriately labelled containers sized to the order, from gram research quantities upward, with packaging chosen to protect the material in transit. As a specialist exporter since 1998, Tech Serve Solutions ships worldwide with the relevant documentation and a Certificate of Analysis.
How do I request a sample or quote?
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Contact Tech Serve Solutions with the product name or CAS 1045855-73-9, your required quantity and destination, and any specification you need. We will respond with availability, lead time, packing options and export details.
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