Thiophene-3-carbonyl chloride
Thiophene-3-carbonyl chloride (CAS 41507-35-1) is a heterocyclic compound with the molecular formula C5H3ClOS and a molecular weight of 146.59 g/mol. It is primarily utilised as a versatile building block in organic synthesis. Its reactivity makes it valuable for introducing the thiophene-3-carbonyl moiety into various molecules, facilitating the construction of complex organic structures for research and development purposes.

Organic Synthesis Intermediate
Serves as a key intermediate in the synthesis of complex organic molecules, particularly those incorporating a thiophene ring. Its acyl chloride functionality readily participates in acylation reactions.
Pharmaceutical Research
Employed in the development of novel pharmaceutical agents where the thiophene scaffold is a desired structural element. It aids in the modification and functionalisation of drug candidates.
Materials Science
Can be utilised in the synthesis of functional materials, such as organic semiconductors or polymers, where thiophene derivatives offer specific electronic or optical properties.
| Molecular weight | 146.59 |
|---|---|
| Empirical formula | C5H3ClOS |
| Assay | 97% |
| Storage temperature | 2-8°C |
| Melting point | 51-54 °C |
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Thiophene-3-carbonyl chloride used for?
+
Thiophene-3-carbonyl chloride is primarily used as a versatile building block in organic synthesis, particularly in the preparation of pharmaceutical intermediates and functional materials.
What is the CAS number and formula for Thiophene-3-carbonyl chloride?
+
The CAS number for Thiophene-3-carbonyl chloride is 41507-35-1, and its empirical formula (Hill notation) is C5H3ClOS.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies Thiophene-3-carbonyl chloride with a purity of 97% (assay). This product is suitable for research and general chemical synthesis purposes; it is not supplied as USP, BP, EP, or pharmaceutical grade.
How should Thiophene-3-carbonyl chloride be handled and stored?
+
Thiophene-3-carbonyl chloride requires careful handling due to its reactive nature. It should be stored under refrigeration at 2-8°C. Refer to the safety data sheet for detailed hazard information and precautionary statements, including P210, P280, P305 + P351 + P338, and P310.
Is Thiophene-3-carbonyl chloride a controlled substance?
+
The provided data does not indicate that Thiophene-3-carbonyl chloride is a controlled substance.
How is Thiophene-3-carbonyl chloride packed, shipped, and exported?
+
Tech Serve Solutions exports fine chemicals globally. Specific packaging and shipping details for Thiophene-3-carbonyl chloride are available upon request and comply with international shipping regulations for hazardous materials.
How can I request a sample or quote for Thiophene-3-carbonyl chloride?
+
To request a sample or a quotation for Thiophene-3-carbonyl chloride, please contact our sales department via the website or direct email, providing your contact details and the quantity required.
▶ Related products

1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis

1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more

3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis

3-Methyl-1,5-pentanediol
Chemical Synthesis

3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis