Thiosalicylic acid
Thiosalicylic acid (CAS: 147-93-3), with the formula HSC₆H₄CO₂H and a molecular weight of 154.19 g/mol, is a key organic building block and sulfur compound. This white to off-white crystalline solid serves as a valuable trapping agent in chemical synthesis, notably in the desulfenylation of 3-indolyl sulfides. It also finds application in the condensation with diamines to form macrocyclic diamides, demonstrating its utility in advanced organic chemistry research and development.
- IUPAC
- 2-Mercaptobenzoic acid
- Synonyms
- 2-Mercaptobenzoic acid
Trapping Agent in Desulfenylation
Thiosalicylic acid acts as an effective trapping agent in the desulfenylation of 3-indolyl sulfides. This application is crucial for specific synthetic pathways in organic chemistry, enabling precise molecular modifications.
Macrocyclic Diamide Synthesis
This compound can be condensed with diamines to yield macrocyclic diamides. This reaction is significant for the construction of complex cyclic structures used in medicinal chemistry and materials science.
Organic Synthesis Intermediate
As an organic building block, thiosalicylic acid is employed in various chemical synthesis processes. Its thiol and carboxylic acid functionalities offer versatile reactivity for creating new molecular architectures.
| Molecular weight | 154.19 |
|---|---|
| Linear formula | HSC6H4CO2H |
| Assay | 97% |
| Application | Trapping agent used in the desulfenylation of 3-indolyl sulfides.1 Condenses with diamines to form macrocyclic diamides.2 |
| Melting point | 162-165 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Thiosalicylic Acid (CAS: 147-93-3) used for?
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Thiosalicylic acid (CAS: 147-93-3) is used as a trapping agent in the desulfenylation of 3-indolyl sulfides and condenses with diamines to form macrocyclic diamides. It is also a general building block for chemical synthesis.
What is the CAS number and formula for Thiosalicylic Acid?
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The CAS number for Thiosalicylic Acid is 147-93-3, and its chemical formula is HSC₆H₄CO₂H.
What grade and purity does Tech Serve Solutions supply for Thiosalicylic Acid?
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Tech Serve Solutions supplies Thiosalicylic Acid with an assay of 97%. This product is intended for research and chemical synthesis purposes; TSS does not represent it as USP, BP, EP, or other pharmacopoeial grades.
How should Thiosalicylic Acid be handled safely?
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Thiosalicylic Acid is classified as a warning substance (GHS07) and may cause skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Handling requires a dust mask type N95 (US), eyeshields, and gloves. Ensure adequate ventilation and avoid dust formation. Refer to the Safety Data Sheet (SDS) for comprehensive handling information.
Is Thiosalicylic Acid a controlled substance?
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The provided data does not indicate that Thiosalicylic Acid (CAS: 147-93-3) is a controlled substance.
How is Thiosalicylic Acid packaged, shipped, and exported?
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Thiosalicylic Acid is carefully packaged to maintain its integrity during transit. We comply with all relevant regulations for shipping and exporting fine chemicals globally.
How can I request a sample or quote for Thiosalicylic Acid?
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To request a sample or a quotation for Thiosalicylic Acid, please contact our sales team via the website or direct email, providing your specific requirements.
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