Thionyl bromide
Thionyl bromide (CAS: 507-16-4), with the linear formula SOBr₂, is a chemical compound offering a molar mass of 207.87 g/mol. It functions as a potent brominating agent in organic synthesis. Its reactivity makes it suitable for specific transformations, including the direct bromination of primary alcohols in fluorous phase reactions. Thionyl bromide is supplied by Tech Serve Solutions for research and synthetic applications.

Bromination Agent
Thionyl bromide is employed as a reagent for the direct bromination of primary alcohols, particularly within fluorous phase chemistry. This application leverages its capability to introduce bromine atoms into organic molecules.
C-X Bond Formation
As a synthetic reagent, thionyl bromide facilitates the formation of carbon-halogen (C-X) bonds, specifically carbon-bromine bonds. This is crucial for the synthesis of various organobromine compounds.
Chemical Synthesis
The compound serves as a versatile tool in general chemical synthesis. Its reactive nature allows for diverse chemical transformations and the creation of complex molecular structures.
| Molecular weight | 207.87 |
|---|---|
| Linear formula | SOBr2 |
| Assay | ≥97.0% (AT) |
| Boiling point | 48 °C/20 mmHg(lit.) |
| Density | 2.683 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.675(lit.) |
| Vapour pressure | 10 mmHg (31 °C) |
| Melting point | −52 °C(lit.) |
| Storage temperature | 2-8°C |
| Application | Direct bromination of primary alcohols in fluorous phase.1 |


Hazard statements
- H312Harmful in contact with skin
- H314Causes severe skin burns and eye damage
- H332Harmful if inhaled
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Transport (UN / ADR) | UN 3264 8 / PGI |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 14-20/21-34 |
| Safety statements (S) | 26-36/37/39-45 |
| Supplemental hazards | Reacts violently with water. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Thionyl bromide used for?
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Thionyl bromide is used in chemical synthesis, primarily as a brominating agent for the direct bromination of primary alcohols in fluorous phase reactions and for C-X bond formation.
What is the CAS number and formula for Thionyl bromide?
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The CAS number for Thionyl bromide is 507-16-4, and its linear formula is SOBr₂.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Thionyl bromide with an assay of ≥97.0% (AT). This product is supplied for research and development purposes and is not represented as USP, BP, EP, or any other pharmacopoeia grade.
How should Thionyl bromide be handled safely?
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Thionyl bromide is a dangerous substance that reacts violently with water and causes severe skin burns and eye damage. It is also harmful if inhaled or swallowed. Handle with appropriate personal protective equipment, including gloves, eye protection, and respiratory protection, in a well-ventilated area or fume hood. Refer to the safety data sheet for comprehensive handling instructions.
How is Thionyl bromide packed, shipped, and exported?
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Thionyl bromide is carefully packed according to international regulations for hazardous materials to ensure safe transport. Tech Serve Solutions, as a global supplier, handles all aspects of shipping and export.
How can I request a sample or quote for Thionyl bromide?
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To request a sample or obtain a quote for Thionyl bromide, please contact the Tech Serve Solutions sales team through our website or by calling our direct line. Please specify the quantity required and your delivery location.
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