L-Proline methyl ester hydrochloride
L-Proline methyl ester hydrochloride (CAS: 2133-40-6), with the molecular formula C6H11NO2 · HCl and a molecular weight of 165.62 g/mol, is a derivative of the amino acid L-proline. This compound serves as a valuable building block in organic synthesis, particularly in the development of peptides and pharmaceutical intermediates. Its specific chemical structure lends itself to various applications within chemical biology and synthesis research.

Peptide Synthesis
L-Proline methyl ester hydrochloride is employed as a protected amino acid derivative in solid-phase and solution-phase peptide synthesis. It facilitates the controlled coupling of proline residues into peptide chains.
Pharmaceutical Intermediates
This compound acts as a key intermediate in the synthesis of various pharmaceutical agents. Its structure can be incorporated into complex drug molecules, contributing to their pharmacological activity.
Chemical Biology Research
In chemical biology, L-Proline methyl ester hydrochloride is used to study proline-containing peptides and proteins. It can be utilized in probes or modified peptides to investigate biological pathways.
Organic Synthesis Building Block
As a versatile building block, it is utilised in a broad range of organic synthesis projects, enabling the creation of novel chemical entities for research and development.
| Molecular weight | 165.62 |
|---|---|
| Empirical formula | C6H11NO2 · HCl |
| Assay | ≥99.0% (AT) |
| Optical activity | [α]20/D −33±2°, c = 1% in H2O |
| Storage temperature | 2-8°C |
| Melting point | 68-78 °C69-71 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
Precautionary statements
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/38 |
| Safety statements (S) | 26-37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is L-Proline methyl ester hydrochloride used for?
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L-Proline methyl ester hydrochloride is primarily used as a building block in peptide synthesis, a key intermediate in the creation of pharmaceutical agents, and in general organic and chemical biology research.
What is the CAS number and chemical formula?
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The CAS number for L-Proline methyl ester hydrochloride is 2133-40-6, and its chemical formula is C6H11NO2 · HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies L-Proline methyl ester hydrochloride with an assay of ≥99.0% (AT). This product is not represented as USP, BP, EP, or pharmacopoeia grade.
How should L-Proline methyl ester hydrochloride be handled and stored?
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This compound is a skin and eye irritant (H315-H319). Handle with appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, and gloves. Store at 2-8°C.
Is L-Proline methyl ester hydrochloride a controlled substance?
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Based on the provided data, L-Proline methyl ester hydrochloride is not listed as a controlled substance.
How is this product packed and shipped?
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Tech Serve Solutions offers L-Proline methyl ester hydrochloride for global export, with packaging suitable for maintaining product integrity during transit. Specific packing details can be provided upon request.
How can I request a sample or quote?
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To request a sample or a quote for L-Proline methyl ester hydrochloride, please contact the Tech Serve Solutions sales team through our website or by phone.
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