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L-Proline methyl ester hydrochloride

CAS 2133-40-6C6H11NO2 · HClChemical Synthesis

L-Proline methyl ester hydrochloride (CAS: 2133-40-6), with the molecular formula C6H11NO2 · HCl and a molecular weight of 165.62 g/mol, is a derivative of the amino acid L-proline. This compound serves as a valuable building block in organic synthesis, particularly in the development of peptides and pharmaceutical intermediates. Its specific chemical structure lends itself to various applications within chemical biology and synthesis research.

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L-Proline methyl ester hydrochloride (C6H11NO2 · HCl) — chemical structure, CAS 2133-40-6; Chemistry, fine chemical supplied by Tech Serve Solutions
Amino Acid DerivativesChemical BiologyChemical SynthesisPeptide ChemistryProline
01 /Applications

Peptide Synthesis

L-Proline methyl ester hydrochloride is employed as a protected amino acid derivative in solid-phase and solution-phase peptide synthesis. It facilitates the controlled coupling of proline residues into peptide chains.

Pharmaceutical Intermediates

This compound acts as a key intermediate in the synthesis of various pharmaceutical agents. Its structure can be incorporated into complex drug molecules, contributing to their pharmacological activity.

Chemical Biology Research

In chemical biology, L-Proline methyl ester hydrochloride is used to study proline-containing peptides and proteins. It can be utilized in probes or modified peptides to investigate biological pathways.

Organic Synthesis Building Block

As a versatile building block, it is utilised in a broad range of organic synthesis projects, enabling the creation of novel chemical entities for research and development.

02 /Properties
Molecular weight165.62
Empirical formulaC6H11NO2 · HCl
Assay≥99.0% (AT)
Optical activity[α]20/D −33±2°, c = 1% in H2O
Storage temperature2-8°C
Melting point68-78 °C69-71 °C(lit.)
03 /Safety & handling
GHS hazard pictogram: Harmful / irritant (GHS07)
Harmful / irritant
Warning

Hazard statements

  • H315Causes skin irritation
  • H319Causes serious eye irritation

Precautionary statements

  • P305IF IN EYES
Protective equipmentdust mask type N95 (US), Eyeshields, Gloves
Water hazard class (WGK, DE)3
Hazard codes (EU)Xi
Risk statements (R)36/38
Safety statements (S)26-37/39

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
2133-40-6
MDL number
MFCD00012708
PubChem substance
24887892
Beilstein registry
3596045
05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is L-Proline methyl ester hydrochloride used for?

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L-Proline methyl ester hydrochloride is primarily used as a building block in peptide synthesis, a key intermediate in the creation of pharmaceutical agents, and in general organic and chemical biology research.

What is the CAS number and chemical formula?

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The CAS number for L-Proline methyl ester hydrochloride is 2133-40-6, and its chemical formula is C6H11NO2 · HCl.

What grade and purity does Tech Serve Solutions supply?

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Tech Serve Solutions supplies L-Proline methyl ester hydrochloride with an assay of ≥99.0% (AT). This product is not represented as USP, BP, EP, or pharmacopoeia grade.

How should L-Proline methyl ester hydrochloride be handled and stored?

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This compound is a skin and eye irritant (H315-H319). Handle with appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, and gloves. Store at 2-8°C.

Is L-Proline methyl ester hydrochloride a controlled substance?

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Based on the provided data, L-Proline methyl ester hydrochloride is not listed as a controlled substance.

How is this product packed and shipped?

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Tech Serve Solutions offers L-Proline methyl ester hydrochloride for global export, with packaging suitable for maintaining product integrity during transit. Specific packing details can be provided upon request.

How can I request a sample or quote?

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To request a sample or a quote for L-Proline methyl ester hydrochloride, please contact the Tech Serve Solutions sales team through our website or by phone.

Need L-Proline methyl ester hydrochloride in a specific grade or volume?