Indole-3-carboxylic acid
Indole-3-carboxylic acid (CAS: 771-50-6; Formula: C9H7NO2; MW: 161.16) is a key heterocyclic building block utilised in chemical synthesis. It serves as a critical reactant in the preparation of various complex organic molecules, including anticancer agents, peptide derivatives, and receptor antagonists. Its indole structure makes it valuable for researchers developing novel therapeutic agents and for advanced chemical research.
- IUPAC
- β-Indolylcarboxylic acid,3-Carboxyindole,3-Indole formic acid,3-Indolylcarboxylic acid,Indole-β-carboxylic acid
- Synonyms
- β-Indolylcarboxylic acid3-Carboxyindole3-Indole formic acid3-Indolylcarboxylic acidIndole-β-carboxylic acid
Preparation of Anticancer Agents
Indole-3-carboxylic acid is a precursor in the synthesis of various anticancer agents, contributing to the development of novel chemotherapeutic compounds.
Synthesis of Peptide Derivatives
This compound is employed as a reactant for creating derivatives of amino acids and peptides, which are important in biochemical research and drug discovery.
Development of Receptor Antagonists
Indole-3-carboxylic acid is utilised in the synthesis of specific receptor antagonists, such as those targeting the serotonin 5-HT4 and 5-HT6 receptors.
Intermediate for Pharmaceutical Research
It serves as a building block for inhibitors of specific biological pathways, including the Hedgehog pathway, and potential therapeutic agents for conditions like Alzheimer's disease.
| Molecular weight | 161.16 |
|---|---|
| Empirical formula | C9H7NO2 |
| Assay | 98% |
| Solubility | 95% ethanol: soluble5%, clear to slightly hazy, light yellow to yellow |
| Application | Reactant for preparation of:• Anticancer agents1• Derivatives of amino acids and peptides2• Serotonin 5-HT4 receptor antagonists3• Primary acylureas4• Inhibitors of Gli1-mediated transcription in the Hedgehog pathway5• Serotonin 5-HT6 antagonists6• Very Late Antigen-4 (VLA-4) sntagonists7• EphB3 receptor tyrosine kinase inhibitors8• Potential Therapeutic Agent for Alzheimer′s Disease9• Vinyl ester pseudotripeptide proteasome inhibitors10 |
| Melting point | 232-234 °C (dec.)(lit.) |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Indole-3-carboxylic acid used for?
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Indole-3-carboxylic acid is primarily used as a reactant in the synthesis of various compounds, including anticancer agents, derivatives of amino acids and peptides, and receptor antagonists. It is a valuable building block for pharmaceutical research and chemical synthesis.
What is the CAS number and chemical formula for Indole-3-carboxylic acid?
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The CAS number for Indole-3-carboxylic acid is 771-50-6, and its chemical formula is C9H7NO2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Indole-3-carboxylic acid with an assay of 98%. TSS does not represent this product as USP, BP, or EP grade.
What are the safety and handling considerations for Indole-3-carboxylic acid?
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Indole-3-carboxylic acid is classified with WGK 2 (Germany). Users should consult the Safety Data Sheet (SDS) for comprehensive handling, storage, and hazard information.
How is Indole-3-carboxylic acid packed, shipped, and exported?
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Indole-3-carboxylic acid is carefully packed to ensure stability and integrity during transit. Tech Serve Solutions exports this chemical globally, adhering to all relevant shipping regulations.
How can I request a sample or quote for Indole-3-carboxylic acid?
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To request a sample or a quotation for Indole-3-carboxylic acid, please contact our sales team via the website or by phone. We will respond promptly with the information you require.
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