Indole-3-acetic hydrazide
Indole-3-acetic hydrazide (CAS 5448-47-5, C10H11N3O) is a heterocyclic organic compound with a molecular weight of 189.21 g/mol. This indole derivative serves as a valuable building block in chemical synthesis. It is primarily utilised as a reactant in the preparation of various biologically active molecules, including antifungal, anticonvulsant, and antibacterial agents, as well as integrin antagonists and antioxidant compounds.
- IUPAC
- 3-Indolylacetic acid hydrazide,NSC 17812,NSC 63799
- Synonyms
- 3-Indolylacetic acid hydrazideIndole-3-acetic acid hydrazideNSC 17812NSC 63799
Antifungal and Antibacterial Agent Synthesis
Indole-3-acetic hydrazide is employed as a key reactant in the synthesis of novel antifungal and antibacterial agents. Its structure facilitates the development of compounds with potential therapeutic applications against microbial infections.
Development of Anticonvulsant Agents
This compound serves as a precursor for the synthesis of anticonvulsant agents. Research indicates its utility in developing molecules aimed at managing seizure disorders.
Preparation of Alpha-4 Integrin Antagonists
Indole-3-acetic hydrazide is used in the preparation of alpha-4 (α4) integrin antagonists. These compounds are of interest for their potential in treating inflammatory and autoimmune diseases.
Synthesis of Antioxidant and Myocardial Protective Agents
It acts as a reactant in the synthesis of antioxidant agents demonstrating myocardial protection properties. This highlights its role in cardiovascular research and drug development.
Fluorescent Analogue Synthesis
Indole-3-acetic hydrazide is a reactant for preparing a fluorescent analogue of UDP-N-acetylglucosamine, useful in biochemical and cellular studies.
| Molecular weight | 189.21 |
|---|---|
| Empirical formula | C10H11N3O |
| Assay | 97% |
| Application | Reactant for preparation of:• Antifungal agents1• Anticonvulsant agents2• Alpha-4 (α4) integrin antagonists3• A fluorescent analogue of UDP-N-acetylglucosamine4• Antioxidant agents with myocardial protection properties5• Antagonist agents of neuropeptide Y receptors6• Antibacterial agents7• Potential monoamine oxidase inhibitors8 |
| Melting point | 142-145 °C(lit.) |
Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Indole-3-acetic hydrazide primarily used for?
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Indole-3-acetic hydrazide is used as a reactant in the preparation of various biologically active compounds, including antifungal agents, anticonvulsant agents, alpha-4 integrin antagonists, fluorescent analogues, antioxidant agents, and neuropeptide Y receptor antagonists.
What are the CAS number and formula for Indole-3-acetic hydrazide?
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The CAS number for Indole-3-acetic hydrazide is 5448-47-5, and its empirical formula (Hill notation) is C10H11N3O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Indole-3-acetic hydrazide with a minimum assay of 97%. This product is not represented as USP, BP, EP, or any other pharmacopoeia grade.
What are the safety and handling considerations for Indole-3-acetic hydrazide?
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Indole-3-acetic hydrazide is classified as harmful if swallowed and causes skin, eye, and respiratory irritation (H302-H315-H319-H335). Handle with appropriate personal protective equipment in a well-ventilated area. Avoid dust formation and inhalation. Refer to the Safety Data Sheet (SDS) for comprehensive handling information.
Is Indole-3-acetic hydrazide a controlled substance?
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The provided data does not indicate that Indole-3-acetic hydrazide is a controlled substance.
How can I request a sample or quote for Indole-3-acetic hydrazide?
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To request a sample or quote for Indole-3-acetic hydrazide, please contact our sales team through the website or by phone. Our team will be happy to assist you with your inquiry.
How is Indole-3-acetic hydrazide packed and exported?
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Indole-3-acetic hydrazide is carefully packed to ensure stability during transit. As a global supplier, Tech Serve Solutions exports this chemical worldwide, adhering to all relevant shipping regulations.
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