L-Proline benzyl ester hydrochloride
L-Proline benzyl ester hydrochloride (CAS: 16652-71-4), with the molecular formula C12H15NO2 · HCl and a molecular weight of 241.71 g/mol, is a valuable amino acid derivative. It finds significant use in the field of peptide chemistry and serves as a chiral auxiliary in asymmetric Diels-Alder reactions. This compound is supplied by Tech Serve Solutions for research and synthesis purposes.

Peptide Synthesis
L-Proline benzyl ester hydrochloride is an important building block in the synthesis of peptides, particularly those containing proline residues. Its protected form allows for controlled coupling reactions in solid-phase and solution-phase peptide synthesis.
Chiral Auxiliary
The compound acts as a chiral auxiliary in asymmetric synthesis. It has been employed in reactions such as the asymmetric Diels-Alder reaction, enabling the stereoselective formation of complex organic molecules.
Chemical Synthesis
As a derivative of the amino acid proline, it is utilised in various organic synthesis pathways where specific stereochemistry or functional group manipulation is required.
| Molecular weight | 241.71 |
|---|---|
| Empirical formula | C12H15NO2 · HCl |
| Assay | 98% |
| Optical activity | [α]20/D −48°, c = 1 in H2O |
| Application | Extensive applications in peptide chemistry and used as a chiral auxiliary in the asymmetric Diels-Alder reaction.1 |
| Melting point | 148-151 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is L-Proline benzyl ester hydrochloride used for?
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L-Proline benzyl ester hydrochloride is primarily used in peptide chemistry and as a chiral auxiliary in asymmetric synthesis, such as the Diels-Alder reaction.
What is the CAS number and chemical formula for L-Proline benzyl ester hydrochloride?
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The CAS number is 16652-71-4, and the chemical formula is C12H15NO2 · HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies L-Proline benzyl ester hydrochloride with an assay of 98%. It is supplied for research and synthesis purposes and is not represented as USP, BP, or EP grade.
What are the safety and handling recommendations for L-Proline benzyl ester hydrochloride?
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When handling L-Proline benzyl ester hydrochloride, it is essential to use personal protective equipment, including eyeshields, gloves, and a type N95 (US) or type P1 (EN143) respirator filter. Refer to the Safety Data Sheet for comprehensive handling information. It is classified under WGK Germany 3.
How is L-Proline benzyl ester hydrochloride typically packed and shipped?
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Tech Serve Solutions carefully packs and exports fine chemicals, including L-Proline benzyl ester hydrochloride, in compliance with international shipping regulations to ensure safe and secure delivery worldwide.
How can I request a sample or a quote for L-Proline benzyl ester hydrochloride?
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To request a sample or obtain a quote for L-Proline benzyl ester hydrochloride, please contact our sales department through the website or by phone.
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