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L-Proline benzyl ester hydrochloride

CAS 16652-71-4C12H15NO2 · HClChemical Synthesis

L-Proline benzyl ester hydrochloride (CAS: 16652-71-4), with the molecular formula C12H15NO2 · HCl and a molecular weight of 241.71 g/mol, is a valuable amino acid derivative. It finds significant use in the field of peptide chemistry and serves as a chiral auxiliary in asymmetric Diels-Alder reactions. This compound is supplied by Tech Serve Solutions for research and synthesis purposes.

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L-Proline benzyl ester hydrochloride (C12H15NO2 · HCl) — chemical structure, CAS 16652-71-4; Chemistry, fine chemical supplied by Tech Serve Solutions
Amino Acid DerivativesChemical BiologyChemical SynthesisPeptide ChemistryProline
01 /Applications

Peptide Synthesis

L-Proline benzyl ester hydrochloride is an important building block in the synthesis of peptides, particularly those containing proline residues. Its protected form allows for controlled coupling reactions in solid-phase and solution-phase peptide synthesis.

Chiral Auxiliary

The compound acts as a chiral auxiliary in asymmetric synthesis. It has been employed in reactions such as the asymmetric Diels-Alder reaction, enabling the stereoselective formation of complex organic molecules.

Chemical Synthesis

As a derivative of the amino acid proline, it is utilised in various organic synthesis pathways where specific stereochemistry or functional group manipulation is required.

02 /Properties
Molecular weight241.71
Empirical formulaC12H15NO2 · HCl
Assay98%
Optical activity[α]20/D −48°, c = 1 in H2O
ApplicationExtensive applications in peptide chemistry and used as a chiral auxiliary in the asymmetric Diels-Alder reaction.1
Melting point148-151 °C(lit.)
03 /Safety & handling
Protective equipmentEyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
16652-71-4
MDL number
MFCD00039002
PubChem substance
24862432
Beilstein registry
3598081
05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is L-Proline benzyl ester hydrochloride used for?

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L-Proline benzyl ester hydrochloride is primarily used in peptide chemistry and as a chiral auxiliary in asymmetric synthesis, such as the Diels-Alder reaction.

What is the CAS number and chemical formula for L-Proline benzyl ester hydrochloride?

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The CAS number is 16652-71-4, and the chemical formula is C12H15NO2 · HCl.

What grade and purity does Tech Serve Solutions supply?

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Tech Serve Solutions supplies L-Proline benzyl ester hydrochloride with an assay of 98%. It is supplied for research and synthesis purposes and is not represented as USP, BP, or EP grade.

What are the safety and handling recommendations for L-Proline benzyl ester hydrochloride?

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When handling L-Proline benzyl ester hydrochloride, it is essential to use personal protective equipment, including eyeshields, gloves, and a type N95 (US) or type P1 (EN143) respirator filter. Refer to the Safety Data Sheet for comprehensive handling information. It is classified under WGK Germany 3.

How is L-Proline benzyl ester hydrochloride typically packed and shipped?

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Tech Serve Solutions carefully packs and exports fine chemicals, including L-Proline benzyl ester hydrochloride, in compliance with international shipping regulations to ensure safe and secure delivery worldwide.

How can I request a sample or a quote for L-Proline benzyl ester hydrochloride?

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To request a sample or obtain a quote for L-Proline benzyl ester hydrochloride, please contact our sales department through the website or by phone.

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