L-Phenylalanine tert-butyl ester hydrochloride
L-Phenylalanine tert-butyl ester hydrochloride (CAS: 15100-75-1) is a hydrochloride salt of the tert-butyl ester derivative of the essential amino acid L-phenylalanine. With a molecular weight of 257.76 g/mol, this compound serves as a valuable building block in organic synthesis. Its primary applications lie in peptide chemistry and the development of novel pharmaceutical intermediates, offering a protected form of phenylalanine for controlled reactions in research and development settings.

Peptide Synthesis
Utilised as a protected amino acid derivative in solid-phase and solution-phase peptide synthesis. The tert-butyl ester group provides orthogonal protection, allowing for selective deprotection strategies during complex peptide chain elongation.
Organic Synthesis Intermediate
Serves as a chiral building block for the synthesis of various organic molecules. Its phenylalanine backbone and protected amine and carboxyl groups enable intricate synthetic pathways in medicinal chemistry and the creation of fine chemicals.
Biochemical Research
Employed in studies involving amino acid metabolism, enzyme inhibition, and the design of peptidomimetics. It provides researchers with a specialised reagent for investigating biological processes at a molecular level.
| Molecular weight | 257.76 |
|---|---|
| Linear formula | C6H5CH2CH(NH2)COOC(CH3)3 · HCl |
| Storage temperature | −20°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is L-Phenylalanine tert-butyl ester hydrochloride used for?
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L-Phenylalanine tert-butyl ester hydrochloride is primarily used as a protected building block in peptide synthesis and as an intermediate in organic synthesis, particularly in medicinal chemistry and biochemical research.
What is the CAS number and chemical formula for L-Phenylalanine tert-butyl ester hydrochloride?
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The CAS number is 15100-75-1 and the linear formula is C<sub>6</sub>H<sub>5</sub>CH<sub>2</sub>CH(NH<sub>2</sub>)COOC(CH<sub>3</sub>)<sub>3</sub> · HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this chemical for research and laboratory use. Specific assay and purity information can be found on the product's Certificate of Analysis. It is not supplied as USP, BP, EP, or other pharmacopoeia grades.
How should L-Phenylalanine tert-butyl ester hydrochloride be handled safely?
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Handling requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used if airborne exposure is possible. Refer to the Safety Data Sheet for comprehensive handling information.
What is the recommended storage temperature?
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The recommended storage temperature for L-Phenylalanine tert-butyl ester hydrochloride is -20°C.
Is this chemical exported or shipped internationally by TSS?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, and L-Phenylalanine tert-butyl ester hydrochloride can be shipped internationally.
How can I request a sample or quote for L-Phenylalanine tert-butyl ester hydrochloride?
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To request a sample or a formal quotation, please contact the Tech Serve Solutions sales team via the website or directly by phone or email.
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