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L-Pipecolic acid

CAS 3105-95-1C6H11NO2Chemical Synthesis

L-Pipecolic acid (CAS: 3105-95-1, C6H11NO2) is a non-proteinogenic amino acid with a molecular weight of 129.16 g/mol. It is a derivative of proline, featuring a six-membered ring. This compound is valued in chemical synthesis and research for its unique structure, finding application in peptide chemistry and as a building block for more complex molecules. Its chiral nature also makes it important in stereoselective synthesis.

IUPAC
(S)-(−)-2-Piperidinecarboxylic acid,L-Homoproline
Synonyms
L-Homoproline(S)-(-)-2-Piperidinecarboxylic acid
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L-Pipecolic acid (C6H11NO2) — chemical structure, CAS 3105-95-1; Chemistry, fine chemical supplied by Tech Serve Solutions
Amino AcidsBiochemicals and ReagentsCell BiologyChemical BiologyChemical SynthesisModified Amino AcidsNutrition ResearchPeptide ChemistryProline Derivatives
01 /Applications

Chemical Synthesis

L-Pipecolic acid serves as a valuable chiral building block in organic synthesis, particularly for creating complex heterocyclic compounds and modified peptides.

Peptide Chemistry

As a non-proteinogenic amino acid, it can be incorporated into peptides to confer unique structural properties and biological activities.

Biochemical Research

Utilised in biochemical and cell biology studies to investigate metabolic pathways or as a component in biochemical assays.

Nutritional Research

Investigated for its potential roles or as a marker in nutrition research due to its structural similarity to proline.

02 /Properties
Molecular weight129.16
Empirical formulaC6H11NO2
Assay≥99.0% (NT)
Optical activity[α]20/D −26±1°, c = 4% in H2O
Melting point272 °C(lit.)
03 /Safety & handling
GHS hazard pictogram: Harmful / irritant (GHS07)
Harmful / irritant
Warning

Hazard statements

  • H315Causes skin irritation
  • H319Causes serious eye irritation
  • H335May cause respiratory irritation

Precautionary statements

  • P261Avoid breathing dust, fume, gas or vapours
  • P305IF IN EYES
Protective equipmentdust mask type N95 (US), Eyeshields, Gloves
Water hazard class (WGK, DE)3
Hazard codes (EU)Xi
Risk statements (R)36/37/38
Safety statements (S)26-36

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
3105-95-1
MDL number
MFCD00005981
PubChem substance
24898330
Beilstein registry
81093
05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is L-Pipecolic acid used for?

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L-Pipecolic acid is primarily used in chemical synthesis as a chiral building block, in peptide chemistry for developing modified peptides, and in biochemical research.

What are the CAS number and formula for L-Pipecolic acid?

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The CAS number for L-Pipecolic acid is 3105-95-1, and its molecular formula is C6H11NO2.

What grade and purity does Tech Serve Solutions supply?

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Tech Serve Solutions supplies L-Pipecolic acid with an assay of ≥99.0% (NT). We do not represent this product as USP, BP, or EP grade.

How should L-Pipecolic acid be handled safely?

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L-Pipecolic acid is classified as irritating to the skin, eyes, and respiratory system (H315, H319, H335). Handle with appropriate personal protective equipment including a dust mask (N95), eyeshields, and gloves. Ensure adequate ventilation.

Is L-Pipecolic acid a controlled substance?

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Based on the provided data, L-Pipecolic acid is not indicated as a controlled substance.

How is L-Pipecolic acid shipped and exported?

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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, adhering to all regulations for the safe and compliant shipment of L-Pipecolic acid worldwide.

How can I request a sample or quote for L-Pipecolic acid?

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Please contact our sales team via the website or direct email to request a sample or a quotation for L-Pipecolic acid.

Need L-Pipecolic acid in a specific grade or volume?