(S)-3-(Tosylamino)-2-piperidone
(S)-3-(Tosylamino)-2-piperidone (CAS: 124288-95-5) is a chiral piperidone derivative with the molecular formula C12H16N2O3S and a molecular weight of 268.33 g/mol. This compound serves as a valuable building block in organic synthesis, particularly for creating complex heterocyclic structures. Its defined stereochemistry makes it suitable for stereoselective synthesis in pharmaceutical and fine chemical research and development.
- IUPAC
- (S)-4-Methyl-N-(2-oxo-3-piperidinyl)benzenesulfonamide,(S)-3-(Toluenesulfonylamino)-2-piperidinone,(S)-3-(Tosylamino)-2-piperidinone,(S)-N-(2-Oxopiperidin-3-yl)-p-toluenesulfonamide
- Synonyms
- (S)-4-Methyl-N-(2-oxo-3-piperidinyl)benzenesulfonamide(S)-3-(Toluenesulfonylamino)-2-piperidinone(S)-N-(2-Oxopiperidin-3-yl)-p-toluenesulfonamide

Chiral Synthesis Intermediate
Utilised as a chiral building block in the synthesis of complex organic molecules, particularly where specific stereochemistry is crucial for biological activity or material properties.
Pharmaceutical Research
A key intermediate for the development of novel pharmaceutical agents, leveraging its piperidone core and tosylamino group for further derivatisation.
Fine Chemical Synthesis
Employed in the production of specialised fine chemicals, contributing to the diversity of chemical scaffolds available for research and industrial applications.
Heterocyclic Chemistry
Serves as a versatile precursor in heterocyclic chemistry, enabling the construction of substituted piperidine and piperidone ring systems.
| Molecular weight | 268.33 |
|---|---|
| Empirical formula | C12H16N2O3S |
| Assay | 97% |
| Melting point | 176-180 °C |

Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (S)-3-(Tosylamino)-2-piperidone used for?
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(S)-3-(Tosylamino)-2-piperidone is primarily used as a chiral building block in organic synthesis, particularly for the development of pharmaceutical intermediates and complex heterocyclic compounds. Its specific stereochemistry is valuable for stereoselective synthesis.
What are the CAS number and molecular formula?
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The CAS number is 124288-95-5 and the molecular formula is C12H16N2O3S.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (S)-3-(Tosylamino)-2-piperidone with a minimum assay of 97%. This product is suitable for research and chemical synthesis purposes. It is not supplied as USP, BP, EP, or any other pharmacopoeia grade.
What are the safety and handling precautions for this compound?
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This compound is classified as a Warning. It may cause respiratory irritation, skin irritation, and serious eye irritation (H315, H319, H335). It is also harmful if swallowed (H302). Always handle with appropriate personal protective equipment in a well-ventilated area. Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. In case of contact with eyes, rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
How is (S)-3-(Tosylamino)-2-piperidone packed and shipped?
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(S)-3-(Tosylamino)-2-piperidone is carefully packed according to industry standards to ensure safe transit. We export globally to meet the needs of researchers and manufacturers worldwide.
How can I request a sample or quote for (S)-3-(Tosylamino)-2-piperidone?
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To request a sample or a quotation, please contact our sales team through the website or by email, providing your specific requirements and shipping details.
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