(S)-3-Amino-5-hexynoic acid hydrochloride
(S)-3-Amino-5-hexynoic acid hydrochloride (CAS: 332064-85-4, C6H9NO2 · HCl) is a chiral building block with a molecular weight of 163.60 g/mol. This compound features a terminal alkyne and an amino acid moiety, making it valuable in organic synthesis. It serves as a key intermediate in the development of novel molecules within chemical biology and peptide chemistry, particularly in constructing unnatural amino acid derivatives for research purposes.

Asymmetric Synthesis
This chiral molecule acts as a crucial building block in asymmetric synthesis, enabling the stereoselective construction of complex organic molecules. Its inherent chirality is vital for creating enantiomerically pure compounds.
Peptide and Amino Acid Chemistry
As an unnatural amino acid derivative, it is employed in peptide chemistry for the synthesis of modified peptides. The presence of the alkyne functionality allows for further conjugation or incorporation into peptide chains via click chemistry.
Chemical Biology Research
This compound is utilised in chemical biology to probe biological systems or develop new molecular probes. The unique combination of an amino acid and an alkyne offers versatile modification possibilities for biochemical studies.
Organic Synthesis Intermediate
It serves as a versatile intermediate in general organic synthesis, providing a functionalized alkyne and an amino group for diverse chemical transformations and the creation of novel organic frameworks.
| Molecular weight | 163.60 |
|---|---|
| Empirical formula | C6H9NO2 · HCl |
| Assay | ≥94.0% (TLC)94% |
| Optical activity | [α]/D +13±1.5°, c = 1 in H2O |
| Storage temperature | 2-8°C |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
Precautionary statements
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (S)-3-Amino-5-hexynoic acid hydrochloride used for?
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(S)-3-Amino-5-hexynoic acid hydrochloride is used in asymmetric synthesis, peptide chemistry, chemical biology research, and as a general intermediate in organic synthesis, particularly for creating unnatural amino acid derivatives and functionalized molecules.
What is the CAS number and formula for (S)-3-Amino-5-hexynoic acid hydrochloride?
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The CAS number is 332064-85-4 and the molecular formula is C6H9NO2 · HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (S)-3-Amino-5-hexynoic acid hydrochloride with an assay of ≥94.0% (TLC), which is 94% purity. This product is not represented as USP, BP, or EP grade.
What are the safety and handling requirements for this chemical?
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This compound is a Warning (GHS07) and causes skin irritation (H315) and serious eye irritation (H319). Wear a dust mask type N95 (US), eyeshields, and gloves. In case of contact with eyes, rinse cautiously with water for several minutes.
How is this chemical typically packaged and shipped?
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Products are typically packaged in appropriate containers for secure transport and exported globally by Tech Serve Solutions. Storage at 2-8°C is recommended.
How can I request a sample or quote for (S)-3-Amino-5-hexynoic acid hydrochloride?
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To request a sample or quote, please contact the Tech Serve Solutions sales team through our website or by phone, providing the product name and CAS number.
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