(S)-3-(Fmoc-amino)-5-hexenoic acid

CAS 270263-04-2C21H21NO4Chemical Synthesis

(S)-3-(Fmoc-amino)-5-hexenoic acid (CAS: 270263-04-2), with the empirical formula C21H21NO4 and a molecular weight of 351.40 g/mol, is a specialised unnatural amino acid derivative. It is a protected beta-amino acid crucial for the synthesis of complex peptides and peptidomimetics. Its primary applications lie in chemical biology and advanced organic synthesis, enabling the construction of novel molecular architectures.

IUPAC: Fmoc-4-vinyl-L-β-homoalanine

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(S)-3-(Fmoc-amino)-5-hexenoic acid (C21H21NO4) — chemical structure, CAS 270263-04-2; Chemistry, fine chemical supplied by Tech Serve Solutions

Beta-Amino AcidsChemical BiologyChemical SynthesisPeptide Chemistry

01 /Applications

Peptide Synthesis

This Fmoc-protected beta-amino acid serves as a valuable building block in the synthesis of modified peptides and peptidomimetics. It allows for the incorporation of non-natural amino acid residues to enhance peptide stability, bioavailability, or receptor binding affinity.

Chemical Biology Research

It is employed in chemical biology to create probes or modified biomolecules for studying biological processes. The unique structure can introduce conformational constraints or specific functionalities into biologically relevant molecules.

Organic Synthesis

The compound is a versatile intermediate in organic synthesis, particularly for developing novel chiral molecules or complex organic structures. The Fmoc protecting group allows for selective deprotection and further functionalisation.

02 /Properties

Molecular weight	351.40
Empirical formula	C21H21NO4
Assay	≥95.0%
Storage temperature	2-8°C

03 /Safety & handling

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

270263-04-2

MDL number

MFCD01861088

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is (S)-3-(Fmoc-amino)-5-hexenoic acid used for?

This compound is primarily used as a building block in peptide synthesis, chemical biology research, and advanced organic synthesis due to its structure as a protected unnatural beta-amino acid.

What are the CAS number and formula for (S)-3-(Fmoc-amino)-5-hexenoic acid?

The CAS number is 270263-04-2, and its empirical formula is C21H21NO4.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies (S)-3-(Fmoc-amino)-5-hexenoic acid with an assay of ≥95.0%. This is a research or technical grade material, and TSS does not represent it as USP, BP, or EP grade.

What are the safety and handling precautions for this chemical?

Handling requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. The compound has a WGK Germany rating of 3, indicating a high hazard level.

How is this product packed, shipped, and exported?

This chemical is stored at 2-8°C. Tech Serve Solutions, established in 1998, is a specialist global supplier and exporter of fine chemicals, capable of handling international shipments.