L-Proline-2-naphthylamide hydrochloride
L-Proline-2-naphthylamide hydrochloride (CAS: 16037-15-3), with the molecular formula C15H16N2O · HCl and a molecular weight of 276.76 g/mol, is a key biochemical reagent. It serves as a chromogenic substrate for enzyme activity assays, particularly for aminopeptidases. This compound is essential in biochemical research and chemical synthesis, offering reliable performance for enzymatic studies and the development of new chemical entities.
- IUPAC
- N-(2-Naphthyl)-L-prolinamide hydrochloride

Enzyme Activity Assays
L-Proline-2-naphthylamide hydrochloride functions as a specific chromogenic substrate for enzymes such as aminopeptidases. Its enzymatic cleavage releases 2-naphthylamine, which can be quantified, allowing for precise measurement of enzyme activity in biological samples and research settings.
Biochemical Research
This compound is utilised in various biochemical research applications, including studies on enzyme kinetics, protein characterisation, and the investigation of biological pathways involving proline-specific enzymes. Its well-defined chemical structure supports reproducible experimental outcomes.
Chemical Synthesis
As a derivative of L-proline, it can be employed as a building block or intermediate in the synthesis of more complex peptides, peptidomimetics, and other organic molecules. Its reactive functional groups allow for diverse chemical modifications.
| Molecular weight | 276.76 |
|---|---|
| Empirical formula | C15H16N2O · HCl |
| Assay | ≥99.0% (TLC) |
| Solubility | acetic acid: water (1:1): soluble50 mg/mL, clear, slightly yellow |
| Storage temperature | −20°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is L-Proline-2-naphthylamide hydrochloride used for?
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L-Proline-2-naphthylamide hydrochloride is primarily used as a chromogenic substrate for the assay of aminopeptidase activity and in general biochemical research and chemical synthesis.
What are the CAS number and formula for L-Proline-2-naphthylamide hydrochloride?
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The CAS number for L-Proline-2-naphthylamide hydrochloride is 16037-15-3, and its molecular formula is C15H16N2O · HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies L-Proline-2-naphthylamide hydrochloride with an assay of ≥99.0% (TLC). This product is not represented as USP, BP, EP, or pharmacopoeia grade.
How should L-Proline-2-naphthylamide hydrochloride be handled safely?
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When handling L-Proline-2-naphthylamide hydrochloride, it is essential to use appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used if airborne exposure is a risk. Dispose of waste according to local regulations.
How is L-Proline-2-naphthylamide hydrochloride shipped and exported?
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Tech Serve Solutions specialises in the global supply and export of fine chemicals, including L-Proline-2-naphthylamide hydrochloride, adhering to all necessary international shipping and customs regulations.
How can I request a sample or quote for L-Proline-2-naphthylamide hydrochloride?
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To request a sample or a detailed quote for L-Proline-2-naphthylamide hydrochloride, please contact the Tech Serve Solutions sales team through our official website or by phone.
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