16-Amino-1-hexadecanethiol hydrochloride
16-Amino-1-hexadecanethiol hydrochloride (CAS: 1263190-70-0; C16H35NS · HCl) is a functional thiol supplied by Tech Serve Solutions. This compound, with a molecular weight of 309.98 g/mol, is primarily utilised for the surface modification of gold nanoparticles. Its longer alkane chain facilitates the formation of stable self-assembled monolayers (SAMs) on gold surfaces, with the terminal amino groups available for further functionalisation with biomaterials.
- IUPAC
- 16-Mercaptohexadecylamine hydrochloride

Gold Nanoparticle Surface Modification
This aminoalkanethiol is employed to introduce amino functionalities onto gold nanoparticle surfaces. The long hydrocarbon chain enhances the stability of the resulting self-assembled monolayer (SAM) through increased van der Waals interactions.
Biomaterial Conjugation
The terminal amino groups on the modified gold surface can readily react with amine-reactive biomolecules, such as proteins, antibodies, or other biological entities, enabling the development of biosensors and diagnostic tools.
Materials Science Research
Utilised in materials science for creating functionalised surfaces and interfaces. Its ability to form stable SAMs on noble metals makes it valuable for advanced research in nanotechnology and surface engineering.
| Molecular weight | 309.98 |
|---|---|
| Empirical formula | C16H35NS · HCl |
| Assay | 96% |
| Form | powder |
| Storage temperature | 2-8°C |
| Application | This aminoalkanethiol can be utilized for the surface modification of gold nanoparticles. The amino groups introduced by the aminoalkanethiols on the gold surface are usually modified with amine reactive materials such as proteins or other biomaterials. The longer alkane chain helps form a more stable self-assembled monolayer (SAM) on a gold surface due to the greater Van-der-Waals forces between alkane chains. |
| Melting point | 68-73 °C |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 16-Amino-1-hexadecanethiol hydrochloride used for?
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16-Amino-1-hexadecanethiol hydrochloride is used for the surface modification of gold nanoparticles, facilitating the formation of stable self-assembled monolayers (SAMs) with terminal amino groups available for further functionalisation.
What are the CAS number and formula for 16-Amino-1-hexadecanethiol hydrochloride?
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The CAS number is 1263190-70-0 and the empirical formula is C16H35NS · HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 16-Amino-1-hexadecanethiol hydrochloride with an assay of 96%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
What are the safety and handling considerations for this product?
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According to available data, this compound has a GHS classification of Hazard Category 3 for WGK Germany. It is a powder with a melting point of 68-73 °C. Always consult the Safety Data Sheet (SDS) before handling and use appropriate personal protective equipment.
How is 16-Amino-1-hexadecanethiol hydrochloride shipped and exported?
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Tech Serve Solutions is a global supplier and exporter of fine chemicals, pharmaceutical intermediates, and laboratory reagents, adhering to all relevant shipping and export regulations.
How can I request a quote or sample?
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Please contact our sales team via the website or direct email to request a quotation or a sample of 16-Amino-1-hexadecanethiol hydrochloride.
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