L-Serine
L-Serine (CAS 56-45-1) is a non-essential amino acid with the molecular formula HOCH<sub>2</sub>CH(NH<sub>2</sub>)CO<sub>2</sub>H and a molecular weight of 105.09 g/mol. This vital amino acid plays a role in the synthesis of proteins, nucleic acids, and phospholipids. It is an essential component for cellular metabolism and is frequently employed in cell culture media and biochemical research due to its biological significance and purity.
- IUPAC
- (S)-2-Amino-3-hydroxypropionic acid
- Synonyms
- (S)-2-Amino-3-hydroxypropionic acidSerineL-Serine

Cell Culture Media Component
L-Serine is a crucial supplement in cell culture media, supporting the growth and proliferation of various cell lines. Its inclusion aids in cellular metabolism and the synthesis of essential biomolecules required for cell viability and function.
Biochemical Research
As a fundamental amino acid, L-Serine is widely utilised in biochemical and biological research. It serves as a building block for proteins and plays a role in signal transduction pathways, making it invaluable for molecular biology studies.
Pharmaceutical Intermediate
L-Serine can serve as an intermediate in the synthesis of various pharmaceutical compounds. Its specific stereochemistry and functional groups make it a valuable starting material for complex organic synthesis.
Nutritional Supplement Research
While not a USP grade product, L-Serine is researched for its potential roles in nutritional science. It is investigated for its contribution to metabolic pathways and its presence in natural sources.
| Molecular weight | 105.09 |
|---|---|
| Linear formula | HOCH2CH(NH2)CO2H |
| Assay | ≥99% (HPLC) |
| Solubility | H2O: soluble50 mg/mL |
| Impurities tested | endotoxin, tested |
| Suitability | suitable for cell culturesuitable for manufacturing use |
| Melting point | 222 °C (dec.)(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 1 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is L-Serine primarily used for?
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L-Serine is primarily used as a component in cell culture media and for biochemical research due to its role in cellular metabolism and protein synthesis.
What is the CAS number and formula for L-Serine?
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The CAS number for L-Serine is 56-45-1, and its linear formula is HOCH<sub>2</sub>CH(NH<sub>2</sub>)CO<sub>2</sub>H.
What grade and purity does Tech Serve Solutions supply for L-Serine?
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Tech Serve Solutions supplies L-Serine with a purity of ≥99% (HPLC). This product is suitable for cell culture and manufacturing use. TSS does not represent this product as USP, BP, or EP grade.
What are the safety considerations when handling L-Serine?
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When handling L-Serine, it is recommended to use safety precautions such as eyeshields and gloves. In environments where dust may be generated, a type N95 (US) or type P1 (EN143) respirator filter should be used. The WGK Germany classification is 1.
Is L-Serine a controlled substance?
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No, L-Serine is not listed as a controlled substance.
How is L-Serine packed and shipped?
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L-Serine is packed according to industry standards to ensure stability and safety during transport and export. Specific packaging details are available upon request.
How can I request a quote or sample for L-Serine?
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To request a quote or sample for L-Serine, please contact our sales team through the website or by phone, providing your specific requirements.
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