L-Serine methyl ester hydrochloride
L-Serine methyl ester hydrochloride (CAS 5680-80-8) is a derivative of the amino acid L-serine, with the formula HOCH2CH(NH2)COOCH3·HCl and a molecular weight of 155.58 g/mol. This compound serves as a valuable building block in chemical synthesis, particularly within peptide chemistry and biochemical research. Its esterified and salt forms make it a useful intermediate for modifying or incorporating serine residues into larger molecules.
Peptide Synthesis
L-Serine methyl ester hydrochloride is employed as a protected amino acid derivative in solid-phase or solution-phase peptide synthesis. It facilitates the controlled introduction of serine residues into peptide chains, allowing for the construction of complex peptides and peptidomimetics.
Chemical Biology Research
This compound is utilised in chemical biology to study protein structure, function, and modification. It can be incorporated into peptides or proteins to investigate enzyme mechanisms, signalling pathways, or to create labelled biomolecules for imaging and diagnostic purposes.
Organic Synthesis Intermediate
As a versatile intermediate, L-Serine methyl ester hydrochloride can be a starting material for the synthesis of various organic compounds. Its reactive ester and amine functionalities can be selectively modified to create novel molecules with potential pharmaceutical or material science applications.
| Molecular weight | 155.58 |
|---|---|
| Linear formula | HOCH2CH(NH2)COOCH3 · HCl |
| Assay | ≥99.0% (AT) |
| Optical activity | [α]20/D +5±0.5°, c = 2% in methanol |
| Optical purity | enantiomeric ratio: ≥99.0:1.0 (GC) |
| Storage temperature | −20°C |
| Melting point | 163 °C (dec.)(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is L-Serine methyl ester hydrochloride used for?
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L-Serine methyl ester hydrochloride (CAS 5680-80-8) is primarily used as a building block in peptide synthesis, a research tool in chemical biology, and as an intermediate in organic synthesis.
What is the CAS number and chemical formula for L-Serine methyl ester hydrochloride?
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The CAS number is 5680-80-8. The linear formula is HOCH2CH(NH2)COOCH3·HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies L-Serine methyl ester hydrochloride with an assay of ≥99.0% (AT). This is a technical grade suitable for research and synthesis; TSS does not represent it as USP, BP, or EP grade.
How should L-Serine methyl ester hydrochloride be handled safely?
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Handle L-Serine methyl ester hydrochloride with appropriate personal protective equipment, including eyeshields and gloves. Use a type N95 (US) or type P1 (EN143) respirator filter in well-ventilated areas, as it may cause irritation. Refer to the Safety Data Sheet for comprehensive handling information.
How is L-Serine methyl ester hydrochloride shipped and exported?
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L-Serine methyl ester hydrochloride is carefully packaged and exported globally by Tech Serve Solutions, adhering to all relevant shipping regulations for chemical compounds.
How can I request a sample or quote for L-Serine methyl ester hydrochloride?
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To request a sample or a quote for L-Serine methyl ester hydrochloride, please use the contact form on our website or reach out to our sales team directly.
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