2-Phenyl-2-imidazoline
2-Phenyl-2-imidazoline (CAS 936-49-2), with the molecular formula C9H10N2 and a molecular weight of 146.19, is a heterocyclic organic compound. It functions primarily as a valuable building block in chemical synthesis. Its notable applications include acting as a catalyst in N-arylation reactions of indoles and facilitating epoxy-carbonyl transformations, showcasing its utility in advanced organic chemistry research and development.
- IUPAC
- 4,5-Dihydro-2-phenyl-1H-imidazole
- Synonyms
- 4,5-Dihydro-2-phenyl-1H-imidazole
Catalyst for N-arylation of Indoles
2-Phenyl-2-imidazoline serves as an effective catalyst for the N-arylation of indoles, a crucial transformation in the synthesis of various pharmaceutical and agrochemical compounds. This application leverages its ability to facilitate carbon-nitrogen bond formation.
Catalyst for Epoxy-Carbonyl Reactions
This compound is also employed as a catalyst in epoxy-carbonyl reactions, promoting ring-opening of epoxides and subsequent reactions with carbonyl compounds. This capability is useful in constructing complex molecular architectures.
Heterocyclic Building Block
As a versatile heterocyclic building block, 2-Phenyl-2-imidazoline can be incorporated into larger molecules. Its structural features make it suitable for the development of novel organic materials and biologically active compounds.
| Molecular weight | 146.19 |
|---|---|
| Empirical formula | C9H10N2 |
| Assay | ≥98.0% (HPLC) |
| Application | Catalyst for: • N-arylation of indoles1• Epoxy-carbonyl reactions2 |
Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H318Causes serious eye damage
- H410Very toxic to aquatic life with long-lasting effects
Precautionary statements
- P273Avoid release to the environment
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P501Dispose of contents and container per local regulations
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Flash point | 151 °C / 303.8 °F |
| Transport (UN / ADR) | UN 3077 9 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn,N |
| Risk statements (R) | 22-38-41-50/53 |
| Safety statements (S) | 26-39-60-61 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Phenyl-2-imidazoline used for?
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2-Phenyl-2-imidazoline is primarily used as a catalyst in organic synthesis, notably for the N-arylation of indoles and epoxy-carbonyl reactions. It also serves as a heterocyclic building block for the synthesis of more complex molecules.
What are the CAS number and formula for 2-Phenyl-2-imidazoline?
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The CAS number for 2-Phenyl-2-imidazoline is 936-49-2, and its molecular formula is C9H10N2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Phenyl-2-imidazoline with an assay of ≥98.0% (HPLC). This product is intended for research and laboratory use and is not represented as USP, BP, or EP grade.
How should 2-Phenyl-2-imidazoline be handled safely?
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Handling 2-Phenyl-2-imidazoline requires stringent safety precautions due to its hazardous nature. It is classified as corrosive and harmful if swallowed, causing skin irritation and serious eye damage. It is also toxic to aquatic life with long-lasting effects. Appropriate personal protective equipment, including eyeshields, face shields, gloves, and suitable respiratory protection, must be used. Ensure adequate ventilation and avoid release to the environment.
Is 2-Phenyl-2-imidazoline a controlled substance?
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The provided data does not indicate that 2-Phenyl-2-imidazoline is a controlled substance.
How is 2-Phenyl-2-imidazoline packed and exported?
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2-Phenyl-2-imidazoline is packed and exported according to international regulations for hazardous materials, including UN 3077 classification. Specific packaging details are available upon request.
How can I request a sample or quote for 2-Phenyl-2-imidazoline?
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To request a sample or quote for 2-Phenyl-2-imidazoline, please contact the Tech Serve Solutions sales team through our website or direct contact information.
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