ICI 118,551 hydrochloride

CAS 72795-19-8C17H27NO2 · HClBiochemicals & Reagents

ICI 118,551 hydrochloride (CAS: 72795-19-8) is a selective beta-2 adrenergic receptor antagonist. This white powder compound, with a molecular weight of 313.86 g/mol and empirical formula C17H27NO2 · HCl, serves as a valuable tool in pharmacological research. It is primarily utilised for investigating the function of beta-2 adrenergic receptors in various biological systems and cellular signalling pathways.

IUPAC: (±)-1-[2,3-(Dihydro-7-methyl-1H-inden-4-yl)oxy]-3-[(1-methylethyl)amino]-2-butanol hydrochloride
Synonyms: C17H27NO2 · HCl(±)-1-[2,3-(Dihydro-7-methyl-1H-inden-4-yl)oxy]-3-[(1-methylethyl)amino]-2-butanol hydrochloride

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ICI 118,551 hydrochloride (C17H27NO2 · HCl) — chemical structure, CAS 72795-19-8; Life Science, fine chemical supplied by Tech Serve Solutions

AdrenergicsAdrenergics - AntagonistsAntagonistsBioactive Small MoleculesBiochemicals and ReagentsCell BiologyGPCR ModulatorsGPCR ProteinsModulators and AntibodiesNeuroscience

01 /Applications

Beta-2 Adrenergic Receptor Research

ICI 118,551 hydrochloride is employed as a selective antagonist to study the physiological roles and mechanisms of beta-2 adrenergic receptors. Its application aids in understanding cellular responses mediated by these receptors in diverse tissues.

Pharmacological Tool

This compound functions as a key pharmacological tool for in vitro and in vivo studies exploring adrenergic pathways. It is instrumental in dissecting the specific contributions of beta-2 adrenoceptors in complex biological processes.

Neuroscience Investigations

Utilised in neuroscience research, ICI 118,551 hydrochloride helps in understanding the impact of beta-2 adrenergic signalling on neuronal function and neurotransmission. It is particularly relevant for studies on the central nervous system.

02 /Properties

Molecular weight	313.86
Empirical formula	C17H27NO2 · HCl
Assay	≥98% (HPLC)
Form	powder
Colour	white
Solubility	H2O: >10 mg/mL

03 /Safety & handling

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

72795-19-8

MDL number

MFCD00153812

05 /Additional specifications

Gene Information	human ... ADRB2(154)
Storage Condition	desiccated

06 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

07 /Frequently asked questions

What is ICI 118,551 hydrochloride used for?

ICI 118,551 hydrochloride is used as a selective beta-2 adrenergic receptor antagonist for pharmacological research, particularly in studies of cell signalling, neuroscience, and adrenergic pathways.

What is the CAS number and formula for ICI 118,551 hydrochloride?

The CAS number is 72795-19-8, and the empirical formula is C17H27NO2 · HCl.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies ICI 118,551 hydrochloride with an assay of ≥98% (HPLC). This product is supplied for research purposes and TSS does not represent it as USP, BP, or EP grade.

What are the safety and handling recommendations for ICI 118,551 hydrochloride?

Handling ICI 118,551 hydrochloride requires appropriate personal protective equipment, including eyeshields, gloves, and a P1 (EN143) or N95 (US) respirator filter. It is classified under WGK Germany 3, indicating a hazard to water.