IC86621

CAS 404009-40-1C12H15NO3Biochemicals & Reagents

IC86621 (CAS: 404009-40-1, C12H15NO3) is an off-white to light tan solid with a molecular weight of 221.25 g/mol. It functions as a potent inhibitor, primarily utilised in biochemical research. Its applications centre on the investigation of cellular processes, particularly those involving DNA-dependent protein kinase (DNA-PK) and related signalling pathways. This compound is supplied by TSS with a purity of ≥98% (HPLC).

IUPAC: 1-(2-Hydroxy-4-morpholin-4-yl-phenyl)ethanone

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IC86621 (C12H15NO3) — chemical structure, CAS 404009-40-1; Life Science, fine chemical supplied by Tech Serve Solutions

Bioactive Small MoleculesBiochemicals and ReagentsCell BiologyEnzyme InhibitorsEnzyme Inhibitors by EnzymeEnzymesInhibitorsand SubstratesKinase/Phosphatase BiologyP to Q

01 /Applications

DNA-PK Inhibition Studies

IC86621 is employed as a research tool to inhibit DNA-dependent protein kinase (DNA-PK). This allows scientists to study the role of DNA-PK in DNA repair mechanisms, cellular signalling, and other critical biological processes.

Cell Signalling Research

This compound serves as a valuable reagent in cell signalling research, particularly in the field of neuroscience. It helps researchers to investigate signalling cascades influenced by DNA-PK activity.

Serine/Threonine Kinase Pathway Investigations

IC86621 is used to explore the involvement of serine/threonine kinases, such as DNA-PK, in various cellular functions. It aids in understanding the regulation of these pathways.

02 /Properties

Molecular weight	221.25
Empirical formula	C12H15NO3
Assay	≥98% (HPLC)
Colour	off-white to light tan
Solubility	DMSO: ≥10 mg/mL
Storage temperature	2-8°C
Melting point	98-100.3 °C

03 /Safety & handling

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

404009-40-1

MDL number

MFCD07370140

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is IC86621 primarily used for?

IC86621 is primarily used as a research chemical for inhibiting DNA-dependent protein kinase (DNA-PK) and investigating cellular signalling pathways, particularly in cell biology and neuroscience research.

What is the CAS number and molecular formula for IC86621?

The CAS number for IC86621 is 404009-40-1, and its molecular formula is C12H15NO3.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies IC86621 with a purity of ≥98% (HPLC). This is a research grade material and not intended for human, animal, or in-vitro diagnostic use. TSS does not represent this product as USP, BP, EP, or pharmacopoeia grade.

How should IC86621 be handled safely?

Handle IC86621 with appropriate personal protective equipment, including eyeshields, gloves, and a type N95 (US) or P1 (EN143) respirator filter. Consult the Safety Data Sheet for detailed handling and hazard information. The compound carries a WGK Germany rating of 3.

How is IC86621 shipped and exported?

IC86621 is typically stored at 2-8°C. Tech Serve Solutions can fulfil global export orders for research and development purposes, adhering to all relevant shipping regulations.