ICI 204,448 hydrochloride

CAS 121264-04-8C23H26Cl2N2O4 · HClBiochemicals & Reagents

ICI 204,448 hydrochloride (CAS: 121264-04-8) is a white solid with a molecular weight of 501.83 g/mol. This compound is primarily utilised as a research tool in cell biology and neuroscience, particularly for investigating cell signaling pathways and the function of opioid receptors. Its properties make it valuable for studies involving GPCR modulators and membrane protein biology.

IUPAC: (±)-1-[2,3-(Dihydro-7-methyl-1H-inden-4-yl)oxy]-3-[(1-methylethyl)amino]-2-butanol hydrochloride,R,S-[3-[1-[[(3,4-Dichlorophenyl)acetyl]methylamino]-2-(1-pyrrolidinyl)ethyl] phenoxy]-acetic acid hydrochloride
Synonyms: C23H26Cl2N2O4 · HCl

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ICI 204,448 hydrochloride (C23H26Cl2N2O4 · HCl) — chemical structure, CAS 121264-04-8; Life Science, fine chemical supplied by Tech Serve Solutions

Bioactive Small MoleculesBiochemicals and ReagentsCell BiologyGPCR ModulatorsGPCR ProteinsModulators and AntibodiesNeurobiologyNeuroscienceOpioid AgonistsOpioids

01 /Applications

Neuroscience Research

Used as a tool compound in neuroscience research to investigate opioid receptor mechanisms and related cellular signaling pathways. Its action as an opioid agonist makes it relevant for studying pain pathways and central nervous system functions.

Cell Signaling Studies

Applicable in cell biology for probing excitatory amino acid and opioid receptor signaling cascades. It aids in understanding the complex interactions within cell membranes and their downstream effects.

GPCR Modulator Research

Serves as a ligand for G protein-coupled receptors (GPCRs), specifically opioid receptors. This facilitates research into GPCR function, modulation, and the development of novel pharmacological agents.

02 /Properties

Molecular weight	501.83
Empirical formula	C23H26Cl2N2O4 · HCl
Form	solid
Colour	white
Solubility	45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: soluble12 mg/mLdilute sodium carbonate: soluble4 mg/mLH2O: soluble4.5 mg/mL

03 /Safety & handling

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

121264-04-8

MDL number

MFCD00153814

05 /Additional specifications

Gene Information	human ... OPRK1(4986)

06 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

07 /Frequently asked questions

What is ICI 204,448 hydrochloride used for?

ICI 204,448 hydrochloride is primarily used in scientific research, particularly in neuroscience and cell biology, for studying opioid receptor function, cell signaling, and as a GPCR modulator.

What is the CAS number and formula for ICI 204,448 hydrochloride?

The CAS number is 121264-04-8 and the empirical formula is C23H26Cl2N2O4 · HCl.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies ICI 204,448 hydrochloride as a research-grade chemical. We do not represent this product as meeting USP, BP, or EP pharmacopoeial standards.

What are the safety and handling considerations for ICI 204,448 hydrochloride?

Handling requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used. The substance is classified with WGK Germany 3.

How is ICI 204,448 hydrochloride packed, shipped, and exported?

ICI 204,448 hydrochloride is carefully packed in accordance with international shipping regulations for chemicals and is exported globally by Tech Serve Solutions.