1,3-Di-Boc-2-(trifluoromethylsulfonyl)guanidine
1,3-Di-Boc-2-(trifluoromethylsulfonyl)guanidine (CAS: 207857-15-6) is a specialized organic compound with the linear formula CF3SO2N=C[NHCO2C(CH3)3]2 and a molecular weight of 391.36 g/mol. This trifylguanidine derivative serves as a valuable reagent in chemical synthesis, particularly in peptide chemistry and guanidine protection/guanidinylation strategies. Its protected nature makes it useful for selective transformations in complex organic molecules.
- IUPAC
- N,N′-Bis(tert-butoxycarboyl)-N′′-trifylguanidine
- Synonyms
- N,N′-Bis(tert-butoxycarboyl)-N′′-trifylguanidine
![1,3-Di-Boc-2-(trifluoromethylsulfonyl)guanidine (CF3SO2N=C[NHCO2C(CH3)3]2) — chemical structure, CAS 207857-15-6; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F207857-15-6.png&w=3840&q=75)
Guanidine Protection and Guanidinylation
This compound acts as a protected guanidine source, facilitating selective introduction or modification of guanidine functionalities within organic synthesis. It is particularly useful in peptide chemistry where precise control over functional group reactions is essential.
Peptide Chemistry Reagent
In the field of peptide synthesis, 1,3-Di-Boc-2-(trifluoromethylsulfonyl)guanidine can be employed to manage the reactivity of guanidine groups, allowing for sequential coupling and protecting strategies.
Chemical Synthesis Intermediate
As a versatile building block, it finds application in broader organic synthesis projects requiring the incorporation of a protected triflylguanidine moiety or for developing novel synthetic methodologies.
| Molecular weight | 391.36 |
|---|---|
| Linear formula | CF3SO2N=C[NHCO2C(CH3)3]2 |
| Assay | ≥95.0% (HPLC) |
| Melting point | 113 °C (dec.)(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1,3-Di-Boc-2-(trifluoromethylsulfonyl)guanidine used for?
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1,3-Di-Boc-2-(trifluoromethylsulfonyl)guanidine is primarily used in chemical synthesis, particularly for guanidine protection/guanidinylation and in peptide chemistry.
What are the CAS number and formula for 1,3-Di-Boc-2-(trifluoromethylsulfonyl)guanidine?
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The CAS number is 207857-15-6 and the linear formula is CF3SO2N=C[NHCO2C(CH3)3]2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 1,3-Di-Boc-2-(trifluoromethylsulfonyl)guanidine with an assay of ≥95.0% (HPLC). We do not represent this product as USP, BP, or EP grade.
How should 1,3-Di-Boc-2-(trifluoromethylsulfonyl)guanidine be handled safely?
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Based on GHS information, this compound may cause skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Handle with appropriate personal protective equipment, including a dust mask (type N95), eyeshields, and gloves, in a well-ventilated area. Avoid breathing dust.
Is this chemical controlled or scheduled?
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The provided data does not indicate that 1,3-Di-Boc-2-(trifluoromethylsulfonyl)guanidine is a controlled or scheduled substance.
How is 1,3-Di-Boc-2-(trifluoromethylsulfonyl)guanidine packed and shipped?
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Products are packed securely according to standard chemical handling procedures and exported globally by Tech Serve Solutions, adhering to all relevant shipping regulations.
How can I request a quote or sample?
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Please contact the Tech Serve Solutions sales team via our website or listed contact details to request a quotation or a sample of 1,3-Di-Boc-2-(trifluoromethylsulfonyl)guanidine.
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