1,3-Di-Z-2-(trifluoromethylsulfonyl)guanidine
1,3-Di-Z-2-(trifluoromethylsulfonyl)guanidine (CAS 207857-19-0) is a specialized organic compound with a molecular weight of 459.40 g/mol. It is primarily employed in chemical synthesis and peptide chemistry for guanidine protection and guanidinylation. This reagent is valued for its role in facilitating complex organic transformations and is supplied by Tech Serve Solutions for advanced research and development applications.
- IUPAC
- 1,3-Bis(benzyloxycarbonyl)-2-(trifluoromethylsulfonyl)guanidine,2-(Trifluoromethylsulfonyl)-1,3-di-Z-guanidine
- Synonyms
- 1,3-Bis(benzyloxycarbonyl)-2-(trifluoromethylsulfonyl)guanidine2-(Trifluoromethylsulfonyl)-1,3-di-Z-guanidine

Chemical Synthesis
This compound serves as a reagent in complex organic synthesis, particularly where selective protection or functionalization of guanidine groups is required. Its unique structure facilitates controlled reactions in multi-step synthetic pathways.
Peptide Chemistry
In peptide synthesis, it is utilised for guanidinylation, enabling the introduction of guanidine functionalities into amino acid residues. This is crucial for constructing peptides with specific biological activities or structural properties.
Guanidine Protection/Guanidinylation
The reagent is designed for the protection and subsequent guanidinylation of amines. The trifluoromethylsulfonyl group offers specific reactivity, making it a valuable tool for protecting guanidine moieties during sensitive synthetic procedures.
Chemical Biology
Its application extends to chemical biology research, where it can be used to synthesise modified biomolecules or probes for studying biological processes. It enables the precise modification of molecules to investigate biological interactions.
| Molecular weight | 459.40 |
|---|---|
| Empirical formula | C18H16F3N3O6S |
| Assay | ≥98.0% (HPLC) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1,3-Di-Z-2-(trifluoromethylsulfonyl)guanidine used for?
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This compound is used in chemical synthesis, peptide chemistry, and chemical biology, primarily for guanidine protection and guanidinylation.
What is the CAS number and formula for this compound?
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The CAS number is 207857-19-0 and the empirical formula is C18H16F3N3O6S.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product with an assay of ≥98.0% (HPLC). We do not represent this product as USP, BP, or EP grade.
What are the safety and handling recommendations for this chemical?
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Based on available data, users should wear eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. The compound is classified with WGK Germany rating 3, indicating a high hazard to water.
Is this chemical available for export or international shipping?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals and laboratory reagents, and this product can be shipped internationally.
How can I request a sample or quote for this product?
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To request a sample or a quote, please contact our sales department through the website or by phone, providing the product name and CAS number (207857-19-0).
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