IC 261
IC 261 (CAS: 186611-52-9), with the empirical formula C18H17NO4 and a molecular weight of 311.33 g/mol, is a yellow powder. This compound serves as a valuable tool in biochemical research, primarily as an inhibitor for casein kinases. Its specific action on these enzymes makes it relevant for studies in cell signaling pathways and related biological processes.
- IUPAC
- 1,3-Dihydro-3-[(2,4,6-trimethoxyphenyl)methylene]-2H-indol-2-one,SU5607
- Synonyms
- 1,3-Dihydro-3-[(2,4,6-trimethoxyphenyl)methylene]-2H-indol-2-one,SU5607

Biochemical Research
IC 261 is utilised in biochemical and cell biology studies as a tool to investigate protein kinase pathways. Its inhibitory properties aid in understanding cell signaling and kinase-specific functions.
Enzyme Inhibition Studies
As an inhibitor of casein kinases (CK), including Casein kinase 1, IC 261 is employed to research enzyme mechanisms and substrate interactions. This is crucial for drug discovery and understanding cellular regulation.
Neuroscience Research
Given its role in cell signaling, IC 261 finds application in neuroscience research, potentially contributing to the understanding of neuronal function and disorders involving kinase pathways.
| Molecular weight | 311.33 |
|---|---|
| Empirical formula | C18H17NO4 |
| Assay | ≥98% (HPLC) |
| Form | powder |
| Colour | yellow |
| Solubility | DMSO: >10 mg/mL |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... CSNK1D(1453), CSNK1E(1454) |
|---|---|
| Storage Condition | protect from light |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is IC 261 used for?
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IC 261 is used in biochemical research, primarily as an inhibitor for casein kinases (CK), including Casein kinase 1, for studies in cell signaling and related biological processes.
What is the CAS number and formula for IC 261?
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The CAS number for IC 261 is 186611-52-9, and its empirical formula is C18H17NO4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies IC 261 with an assay of ≥98% (HPLC). We do not represent this product as USP, BP, EP, or pharmaceutical grade.
How should IC 261 be handled and stored?
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When handling IC 261, it is essential to use personal protective equipment including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is also recommended. Store this compound protected from light.
Is IC 261 a controlled substance?
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The provided data does not indicate that IC 261 is a controlled substance.
How is IC 261 packed, shipped, and exported?
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IC 261 is supplied as a yellow powder. Tech Serve Solutions can export this chemical globally, adhering to all relevant shipping regulations.
How can I request a quote or sample for IC 261?
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To request a quote or a sample of IC 261, please contact our sales department through the website or by phone. Our team will be pleased to assist you.
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