2-Phenylindole-3-carboxaldehyde
2-Phenylindole-3-carboxaldehyde (CAS: 25365-71-3), with the molecular formula C15H11NO and a molecular weight of 221.25 g/mol, is a key organic building block. This indole derivative functions as a versatile reactant in the synthesis of various biologically active compounds. Its primary applications lie in the preparation of potential anticancer agents, anti-inflammatory drugs, and antimicrobial compounds, underscoring its significance in medicinal chemistry research and development.
- IUPAC
- 3-Formyl-2-phenylindole
Synthesis of Anticancer Agents
Used as a reactant in the preparation of pyridyl-ethenyl-indoles, which are investigated as potential anticancer immunomodulators. It also serves in the synthesis of benzofuranone-attached indole derivatives being studied as PI3K inhibitors.
Development of Antimicrobial Compounds
Acts as a starting material for pyrimidinones synthesized via the Biginelli reaction, evaluated for their antimicrobial properties. It is also employed in the creation of indole thiophene chalcones with demonstrated antimicrobial activity.
Preparation of Anti-inflammatory Agents
Serves as a precursor for [(phenyl)pyrazolyl]indole derivatives and oxazolylindoles, both classes of compounds investigated for their anti-inflammatory and analgesic effects.
Creation of Novel Antiandrogens
Utilised in the synthesis of ionone-based chalcones, which are explored as novel antiandrogen agents.
| Molecular weight | 221.25 |
|---|---|
| Empirical formula | C15H11NO |
| Assay | 97% |
| Application | Reactant for preparation of: • Tryptophan dioxygenase inhibitors pyridyl-ethenyl-indoles as potential anticancer immunomodulators1• Pyrimidinones via Biginelli reaction as antimicrobial agents2• [(phenyl)pyrazolyl]indole derivatives as antiinflammatory agents and analgesics3• Indole thiophene chalcones via Claisen-Schmidt condensation as antimicrobial and antioxidant agents4• Benzofuranone attached indole derivatives as PI3K inhibitors5• Ionone-based chalcones as novel antiandrogens6• Oxazolylindoles as antiinflammatory agents for edema7 |
| Melting point | 249-253 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Phenylindole-3-carboxaldehyde used for?
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2-Phenylindole-3-carboxaldehyde is primarily used as a reactant in organic synthesis for the preparation of various biologically active compounds, including potential anticancer, anti-inflammatory, and antimicrobial agents.
What is the CAS number and molecular formula of 2-Phenylindole-3-carboxaldehyde?
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The CAS number is 25365-71-3 and the molecular formula is C15H11NO.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Phenylindole-3-carboxaldehyde with a minimum purity of 97%. This product is intended for research and laboratory use and is not supplied as USP, BP, or EP grade.
How should 2-Phenylindole-3-carboxaldehyde be handled safely?
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Handle with appropriate personal protective equipment, including a dust mask type N95, eyeshields, and gloves. Ensure good ventilation. Avoid breathing dust. This compound is classified as an irritant to skin, eyes, and the respiratory tract (H315, H319, H335).
Is this product available for export?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including 2-Phenylindole-3-carboxaldehyde, and can accommodate export requests.
How can I request a sample or quote?
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To request a sample or a quote for 2-Phenylindole-3-carboxaldehyde, please contact our sales department through the website or by phone.
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