Fmoc-Glu(OtBu)-OPfp

CAS 86061-04-3C30H26F5NO6Chemical Synthesis

Fmoc-Glu(OtBu)-OPfp (CAS 86061-04-3) is a protected derivative of glutamic acid, with the chemical formula C30H26F5NO6 and a molecular weight of 591.52 g/mol. This compound serves as a key building block in solid-phase peptide synthesis. It features Fmoc protection for the alpha-amino group, a tert-butyl ester for the gamma-carboxyl group, and a pentafluorophenyl ester for the alpha-carboxyl group, facilitating controlled peptide chain elongation.

IUPAC: Fmoc-L-glutamic acid 5-tert-butyl 1-(pentafluorophenyl) ester

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Fmoc-Glu(OtBu)-OPfp (C30H26F5NO6) — chemical structure, CAS 86061-04-3; Chemistry, fine chemical supplied by Tech Serve Solutions

Amino Acid DerivativesChemical BiologyChemical SynthesisGlutamic AcidPeptide Chemistry

01 /Applications

Peptide Synthesis

Fmoc-Glu(OtBu)-OPfp is widely employed in solid-phase peptide synthesis (SPPS) using Fmoc chemistry. Its orthogonal protecting groups allow for selective deprotection and coupling steps, essential for constructing complex peptide sequences.

Chemical Biology Research

This derivative is utilised in chemical biology to synthesise modified peptides or peptidomimetics. These can be used to study protein-protein interactions, enzyme mechanisms, or as tools for biological probes.

Custom Peptide Production

As a reliable reagent, Fmoc-Glu(OtBu)-OPfp is instrumental in the custom synthesis of peptides for pharmaceutical research, diagnostic development, and various biotechnological applications.

02 /Properties

Molecular weight	591.52
Empirical formula	C30H26F5NO6
Assay	≥98.0%
Storage temperature	2-8°C

03 /Safety & handling

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

86061-04-3

MDL number

MFCD00065647

Beilstein registry

3642680

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is Fmoc-Glu(OtBu)-OPfp used for?

Fmoc-Glu(OtBu)-OPfp is primarily used as a protected amino acid derivative in solid-phase peptide synthesis (SPPS) for the incorporation of glutamic acid residues with specific side-chain protection.

What is the CAS number and formula for Fmoc-Glu(OtBu)-OPfp?

The CAS number is 86061-04-3, and the empirical formula is C30H26F5NO6.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies Fmoc-Glu(OtBu)-OPfp with an assay of ≥98.0%. This product is intended for research and laboratory use and is not represented as USP, BP, EP, or pharmacopoeia grade.

How should Fmoc-Glu(OtBu)-OPfp be handled and stored?

Handle Fmoc-Glu(OtBu)-OPfp with appropriate personal protective equipment, including eyeshields and gloves. It should be stored at 2-8°C. Refer to the safety data sheet for detailed handling procedures and hazard information.

Is Fmoc-Glu(OtBu)-OPfp a controlled substance?

The provided data does not indicate that Fmoc-Glu(OtBu)-OPfp is a controlled substance.

How is Fmoc-Glu(OtBu)-OPfp shipped?

Fmoc-Glu(OtBu)-OPfp is carefully packed and exported by Tech Serve Solutions, adhering to all necessary regulations for the safe transport of fine chemicals.

How can I request a quote or sample?

To request a quote or a sample of Fmoc-Glu(OtBu)-OPfp, please contact our sales department via the details provided on the Tech Serve Solutions website.