Fmoc-Glu-OAll
Fmoc-Glu-OAll (CAS: 144120-54-7), with the molecular formula C23H23NO6 and a molecular weight of 409.43 g/mol, is a protected amino acid derivative. It is primarily utilised in peptide synthesis and related chemical research. This compound serves as a crucial building block for incorporating glutamic acid residues into peptide chains, with the Fmoc group offering facile deprotection under mild basic conditions and the allyl ester protecting the side chain carboxyl group, allowing for orthogonal deprotection strategies.
- IUPAC
- Fmoc-L-glutamic acid 1-allyl ester
Peptide Synthesis
Fmoc-Glu-OAll is a key reagent in solid-phase and solution-phase peptide synthesis. The N-terminal Fmoc protection and the allyl ester protection of the glutamic acid side chain enable selective incorporation into complex peptide sequences.
Chemical Biology Research
This derivative finds application in chemical biology for constructing modified peptides with specific functionalities. The orthogonal protection allows for selective manipulation and conjugation of the peptide.
Organic Synthesis
As a versatile building block, Fmoc-Glu-OAll is employed in various organic synthesis pathways where protected glutamic acid moieties are required. Its well-defined protecting groups facilitate controlled synthetic routes.
| Molecular weight | 409.43 |
|---|---|
| Empirical formula | C23H23NO6 |
| Assay | ≥99.0% (HPLC) |
| Optical activity | [α]20/D −20.0±2°, c = 1% in DMF |
| Storage temperature | 2-8°C |
| Melting point | 118-122 °C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Fmoc-Glu-OAll used for?
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Fmoc-Glu-OAll is primarily used as a protected amino acid building block in peptide synthesis and for applications in chemical biology and organic synthesis requiring the controlled incorporation of glutamic acid.
What are the CAS number and formula for Fmoc-Glu-OAll?
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The CAS number for Fmoc-Glu-OAll is 144120-54-7, and its molecular formula is C23H23NO6.
What grade and purity does Tech Serve Solutions supply for Fmoc-Glu-OAll?
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Tech Serve Solutions supplies Fmoc-Glu-OAll with an assay of ≥99.0% (HPLC). This product is intended for research and laboratory use and is not represented as USP, BP, EP, or pharmacopoeia grade.
How should Fmoc-Glu-OAll be handled and stored?
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Fmoc-Glu-OAll should be handled with appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used if necessary. It should be stored at 2-8°C.
Is Fmoc-Glu-OAll a controlled substance?
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The provided data does not indicate that Fmoc-Glu-OAll is a controlled substance.
How is Fmoc-Glu-OAll shipped by Tech Serve Solutions?
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Fmoc-Glu-OAll is carefully packed and exported by Tech Serve Solutions, adhering to all relevant shipping regulations for fine chemicals. Storage at 2-8°C is recommended during transit.
How can I request a quote or sample for Fmoc-Glu-OAll?
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To request a quote or sample for Fmoc-Glu-OAll, please contact our sales department through the website or direct inquiry channels.
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