Fmoc-Gly-OPfp
Fmoc-Gly-OPfp (CAS: 86060-85-7), with the molecular formula C23H14F5NO4 and a molecular weight of 463.35 g/mol, is a key reagent in peptide synthesis. As a derivative of glycine, it facilitates the introduction of the glycine residue into peptide chains using the Fmoc protection strategy. Its pentafluorophenyl ester moiety enhances reactivity, making it a valuable tool in chemical biology and synthesis.
- IUPAC
- Fmoc-glycine pentafluorophenyl ester

Peptide Synthesis
Fmoc-Gly-OPfp serves as an activated building block for solid-phase and solution-phase peptide synthesis. Its role is to efficiently couple the Fmoc-protected glycine residue to a growing peptide chain.
Chemical Biology Research
This compound is employed in the synthesis of modified peptides and peptidomimetics for studying biological processes. It allows for precise incorporation of glycine units in complex molecular architectures.
Organic Synthesis Reagent
Beyond peptide chemistry, Fmoc-Gly-OPfp can be utilised in various organic synthesis pathways requiring the introduction of an N-protected glycine moiety with enhanced reactivity.
| Molecular weight | 463.35 |
|---|---|
| Empirical formula | C23H14F5NO4 |
| Assay | ≥97.0% (HPLC) |
| Storage temperature | 2-8°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Fmoc-Gly-OPfp used for?
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Fmoc-Gly-OPfp (CAS: 86060-85-7) is primarily used as an activated building block in Fmoc-based peptide synthesis, enabling the efficient coupling of the Fmoc-protected glycine residue.
What are the CAS number and formula for Fmoc-Gly-OPfp?
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The CAS number for Fmoc-Gly-OPfp is 86060-85-7, and its empirical formula is C23H14F5NO4.
What grade and purity does Tech Serve Solutions supply for Fmoc-Gly-OPfp?
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Tech Serve Solutions supplies Fmoc-Gly-OPfp with a purity of ≥97.0% as determined by HPLC. This product is not designated as USP, BP, or EP grade.
How should Fmoc-Gly-OPfp be handled and stored?
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Handling requires appropriate personal protective equipment, including eyeshields and gloves. A P1 filter respirator is recommended. This compound is classified under WGK 3 in Germany and should be stored at 2-8°C.
Is Fmoc-Gly-OPfp a controlled substance?
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Based on the provided data, there is no indication that Fmoc-Gly-OPfp is a controlled substance.
How are Tech Serve Solutions' chemicals packed, shipped, and exported?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, ensuring appropriate packaging for safe transport and compliance with international shipping regulations.
How can I request a sample or quote for Fmoc-Gly-OPfp?
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To request a sample or a quote for Fmoc-Gly-OPfp, please contact the Tech Serve Solutions sales team through the official website or designated contact channels.
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