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Fmoc-Gly-OPfp

CAS 86060-85-7C23H14F5NO4Chemical Synthesis

Fmoc-Gly-OPfp (CAS: 86060-85-7), with the molecular formula C23H14F5NO4 and a molecular weight of 463.35 g/mol, is a key reagent in peptide synthesis. As a derivative of glycine, it facilitates the introduction of the glycine residue into peptide chains using the Fmoc protection strategy. Its pentafluorophenyl ester moiety enhances reactivity, making it a valuable tool in chemical biology and synthesis.

IUPAC
Fmoc-glycine pentafluorophenyl ester
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Fmoc-Gly-OPfp (C23H14F5NO4) — chemical structure, CAS 86060-85-7; Chemistry, fine chemical supplied by Tech Serve Solutions
Amino Acid DerivativesChemical BiologyChemical SynthesisGlycinePeptide Chemistry
01 /Applications

Peptide Synthesis

Fmoc-Gly-OPfp serves as an activated building block for solid-phase and solution-phase peptide synthesis. Its role is to efficiently couple the Fmoc-protected glycine residue to a growing peptide chain.

Chemical Biology Research

This compound is employed in the synthesis of modified peptides and peptidomimetics for studying biological processes. It allows for precise incorporation of glycine units in complex molecular architectures.

Organic Synthesis Reagent

Beyond peptide chemistry, Fmoc-Gly-OPfp can be utilised in various organic synthesis pathways requiring the introduction of an N-protected glycine moiety with enhanced reactivity.

02 /Properties
Molecular weight463.35
Empirical formulaC23H14F5NO4
Assay≥97.0% (HPLC)
Storage temperature2-8°C
03 /Safety & handling
Protective equipmentEyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
86060-85-7
MDL number
MFCD00037641
Beilstein registry
4219023
05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is Fmoc-Gly-OPfp used for?

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Fmoc-Gly-OPfp (CAS: 86060-85-7) is primarily used as an activated building block in Fmoc-based peptide synthesis, enabling the efficient coupling of the Fmoc-protected glycine residue.

What are the CAS number and formula for Fmoc-Gly-OPfp?

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The CAS number for Fmoc-Gly-OPfp is 86060-85-7, and its empirical formula is C23H14F5NO4.

What grade and purity does Tech Serve Solutions supply for Fmoc-Gly-OPfp?

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Tech Serve Solutions supplies Fmoc-Gly-OPfp with a purity of ≥97.0% as determined by HPLC. This product is not designated as USP, BP, or EP grade.

How should Fmoc-Gly-OPfp be handled and stored?

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Handling requires appropriate personal protective equipment, including eyeshields and gloves. A P1 filter respirator is recommended. This compound is classified under WGK 3 in Germany and should be stored at 2-8°C.

Is Fmoc-Gly-OPfp a controlled substance?

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Based on the provided data, there is no indication that Fmoc-Gly-OPfp is a controlled substance.

How are Tech Serve Solutions' chemicals packed, shipped, and exported?

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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, ensuring appropriate packaging for safe transport and compliance with international shipping regulations.

How can I request a sample or quote for Fmoc-Gly-OPfp?

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To request a sample or a quote for Fmoc-Gly-OPfp, please contact the Tech Serve Solutions sales team through the official website or designated contact channels.

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