Fmoc-Glu(OBzl)-OH

CAS 123639-61-2C27H25NO6Chemical Synthesis

Fmoc-Glu(OBzl)-OH (CAS: 123639-61-2), with the molecular formula C27H25NO6 and a molecular weight of 459.49 g/mol, is a protected amino acid derivative. It serves as a crucial building block in solid-phase peptide synthesis (SPPS) and other organic synthesis applications. This compound is essential for introducing a protected glutamic acid residue into peptide chains, allowing for controlled chain elongation and modification in research and development settings.

IUPAC: Fmoc-L-glutamic acid 5-benzyl ester
Synonyms: Fmoc-L-glutamic acid 5-benzyl ester

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Fmoc-Glu(OBzl)-OH (C27H25NO6) — chemical structure, CAS 123639-61-2; Chemistry, fine chemical supplied by Tech Serve Solutions

Amino Acid DerivativesAnalytical StandardsAnalytical/ChromatographyChemical BiologyChemical SynthesisFM - FZGlutamic AcidPeptide Chemistry More...

01 /Applications

Peptide Synthesis

Fmoc-Glu(OBzl)-OH is extensively used in Fmoc-based solid-phase peptide synthesis to incorporate glutamic acid residues. The benzyl ester protects the side-chain carboxyl group, preventing unwanted reactions during peptide assembly.

Organic Synthesis Intermediate

Beyond peptide chemistry, this compound acts as a versatile intermediate in the synthesis of complex organic molecules. Its functional groups allow for diverse chemical transformations in research laboratories.

Chemical Biology Research

In chemical biology, Fmoc-Glu(OBzl)-OH is employed in the construction of modified peptides or peptidomimetics for studying biological processes or developing new therapeutic agents.

02 /Properties

Molecular weight	459.49
Empirical formula	C27H25NO6
Assay	≥98.0% (HPLC)
Optical activity	[α]20/D +12.0±2.5°, c = 1% in chloroform
Storage temperature	2-8°C

03 /Safety & handling

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

123639-61-2

MDL number

MFCD00065642

Beilstein registry

3576722

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is Fmoc-Glu(OBzl)-OH used for?

Fmoc-Glu(OBzl)-OH is primarily used as a protected amino acid building block in Fmoc-based solid-phase peptide synthesis and as an intermediate in organic synthesis and chemical biology research.

What is the CAS number and molecular formula for Fmoc-Glu(OBzl)-OH?

The CAS number is 123639-61-2 and the molecular formula is C27H25NO6.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies Fmoc-Glu(OBzl)-OH with an assay of ≥98.0% (HPLC). We do not represent this product as USP, BP, EP, or other pharmacopoeia grades.

What are the safety and handling recommendations for Fmoc-Glu(OBzl)-OH?

Recommended personal protective equipment includes eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used. The compound has a WGK rating of 3 in Germany, indicating a high hazard.

How is Fmoc-Glu(OBzl)-OH typically shipped and exported?

Fmoc-Glu(OBzl)-OH is stored at 2-8°C. We expertly handle packaging and export procedures for this chemical to research and industrial clients globally.