Fmoc-Gln-OH
Fmoc-Gln-OH (CAS 71989-20-3), with the molecular formula C20H20N2O5, is a protected amino acid derivative crucial for peptide synthesis. It is widely employed in solid-phase and solution-phase peptide synthesis to introduce glutamine residues, offering protection of the alpha-amino group via the Fmoc (fluorenylmethyloxycarbonyl) moiety. This compound facilitates the controlled assembly of peptide chains for research and development in various chemical and biological disciplines.
- IUPAC
- Fmoc-L-glutamine
Peptide Synthesis
Fmoc-Gln-OH is a fundamental building block in both solid-phase and solution-phase peptide synthesis. It enables the regioselective incorporation of L-glutamine into peptide sequences, preserving the integrity of the glutamine side chain during synthesis.
Chemical Biology Research
This derivative is utilized in the construction of peptides and peptidomimetics for investigating biological processes, protein interactions, and developing novel therapeutic agents. Its use allows for precise control over peptide structure and function.
Organic Synthesis
As a protected amino acid, Fmoc-Gln-OH serves as a valuable reagent in complex organic synthesis pathways. It allows for controlled elaboration of molecules containing amino acid motifs, finding application in the development of new chemical entities.
| Molecular weight | 368.38 |
|---|---|
| Empirical formula | C20H20N2O5 |
| Assay | ≥95.0% (T) |
| Optical activity | [α]20/D −19.0±1°, c = 1% in DMF |
| Storage temperature | 2-8°C |
| Melting point | 220 °C (dec.)(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Fmoc-Gln-OH used for?
+
Fmoc-Gln-OH is primarily used as a protected amino acid derivative in peptide synthesis, enabling the controlled incorporation of glutamine residues into peptide chains for research in chemical biology and organic synthesis.
What is the CAS number and formula for Fmoc-Gln-OH?
+
The CAS number for Fmoc-Gln-OH is 71989-20-3, and its empirical formula is C20H20N2O5.
What grade and purity does Tech Serve Solutions supply for Fmoc-Gln-OH?
+
Tech Serve Solutions supplies Fmoc-Gln-OH with a purity of ≥95.0% (T). We do not represent this product as meeting USP, BP, EP, or other pharmacopoeial standards.
What are the safety considerations when handling Fmoc-Gln-OH?
+
Handling Fmoc-Gln-OH requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or P1 (EN143) respirator filter is recommended. It has a GHS hazard classification of WGK 2 in Germany.
How is Fmoc-Gln-OH typically stored and shipped?
+
Fmoc-Gln-OH is typically stored at 2-8°C. Tech Serve Solutions ensures appropriate packaging for safe export and global distribution.
How can I request a quote or sample for Fmoc-Gln-OH?
+
To request a quote or sample of Fmoc-Gln-OH, please contact our sales department via the website or direct email, providing your specific requirements and shipping details.
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis