Fmoc-Glu(OAll)-OH
Fmoc-Glu(OAll)-OH (CAS 133464-46-7) is a derivative of glutamic acid with the empirical formula C23H23NO6 and a molecular weight of 409.43 g/mol. This compound is primarily utilised in peptide synthesis and chemical biology research. Its structure incorporates the Fmoc protecting group on the amine and an allyl ester on the side-chain carboxyl group of glutamic acid, facilitating controlled deprotection strategies in solid-phase peptide synthesis.
- IUPAC
- Fmoc-L-glutamic acid 5-allyl ester
Peptide Synthesis
Fmoc-Glu(OAll)-OH serves as a protected glutamic acid building block in solid-phase peptide synthesis (SPPS). The orthogonal protecting groups (Fmoc and OAll) allow for selective removal during synthesis, enabling the construction of complex peptide sequences.
Chemical Biology
This derivative can be employed in chemical biology to introduce modified glutamic acid residues into peptides or proteins. Its unique side-chain protection facilitates the study of protein-peptide interactions or the development of bioactive peptides.
Organic Synthesis
As a functionalised amino acid, Fmoc-Glu(OAll)-OH is a valuable reagent in organic synthesis for creating novel molecules and exploring diverse chemical pathways.
| Molecular weight | 409.43 |
|---|---|
| Empirical formula | C23H23NO6 |
| Assay | ≥96.0% (HPLC) |
| Optical activity | [α]20/D −16.5±2°, c = 1% in DMF |
| Storage temperature | 2-8°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Fmoc-Glu(OAll)-OH used for?
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Fmoc-Glu(OAll)-OH is primarily used as a building block in solid-phase peptide synthesis and in chemical biology research to introduce a protected glutamic acid residue into peptides and other biomolecules.
What is the CAS number and chemical formula for Fmoc-Glu(OAll)-OH?
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The CAS number for Fmoc-Glu(OAll)-OH is 133464-46-7, and its empirical formula is C23H23NO6.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Fmoc-Glu(OAll)-OH with an assay of ≥96.0% determined by HPLC. We do not represent this product as USP, BP, or EP grade.
How should Fmoc-Glu(OAll)-OH be handled and stored?
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Handle Fmoc-Glu(OAll)-OH with appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. Store the compound at 2-8°C.
Is Fmoc-Glu(OAll)-OH a hazardous substance?
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According to GHS, this compound has a WGK (Germany) of 3, indicating it is hazardous. Always consult the safety data sheet for comprehensive handling information and precautions.
How are your products packed, shipped, and exported?
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Tech Serve Solutions specialises in the global supply and export of fine chemicals, ensuring products are securely packed and meet international shipping regulations.
How can I request a sample or quote for Fmoc-Glu(OAll)-OH?
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To request a sample or obtain a quote for Fmoc-Glu(OAll)-OH, please contact our sales department through the website or by phone.
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