Fmoc-Gln(Tmob)-OH
Nα-Fmoc-Nδ-(2,4,6-trimethoxybenzyl)-L-glutamine (CAS: 120658-64-2), with the molecular formula C30H32N2O8 and a molecular weight of 548.58 g/mol, is a protected amino acid derivative essential in peptide synthesis. This compound is frequently employed in solid-phase peptide synthesis (SPPS) and solution-phase methods for constructing complex peptide chains, particularly where glutamine residues require specific protection during coupling steps.
- IUPAC
- Nα-Fmoc-Nδ-(2,4,6-trimethoxybenzyl)-L-glutamine
Peptide Synthesis
This Fmoc-protected glutamine derivative is a crucial building block for solid-phase peptide synthesis (SPPS). The Tmob protecting group on the side chain offers selective deprotection conditions, facilitating controlled peptide chain elongation.
Chemical Biology Research
It serves as a valuable reagent in chemical biology for the synthesis of peptides with modified glutamine residues. These modified peptides can be used to study protein-ligand interactions, enzyme activity, and other biological processes.
Analytical Standards
As a well-defined chemical entity, Fmoc-Gln(Tmob)-OH can be utilised as an analytical standard in chromatography and other analytical techniques for quality control and method development in peptide-related research and production.
| Molecular weight | 548.58 |
|---|---|
| Empirical formula | C30H32N2O8 |
| Assay | ≥98.0% (TLC) |
| Storage temperature | 2-8°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Fmoc-Gln(Tmob)-OH used for?
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Fmoc-Gln(Tmob)-OH is primarily used as a protected amino acid derivative in solid-phase and solution-phase peptide synthesis. The Tmob group protects the glutamine side chain during peptide coupling reactions.
What are the CAS number and molecular formula for Fmoc-Gln(Tmob)-OH?
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The CAS number for Fmoc-Gln(Tmob)-OH is 120658-64-2, and its molecular formula is C30H32N2O8.
What grade and purity does Tech Serve Solutions supply for Fmoc-Gln(Tmob)-OH?
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Tech Serve Solutions supplies Fmoc-Gln(Tmob)-OH with a purity of ≥98.0% (TLC). This product is intended for research and laboratory use. TSS does not represent this product as USP, BP, EP, or pharmacopoeia grade.
What are the safety and handling recommendations for Fmoc-Gln(Tmob)-OH?
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Handling Fmoc-Gln(Tmob)-OH requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. The substance is classified with a WGK Germany of 3, indicating it is hazardous to water.
How is Fmoc-Gln(Tmob)-OH shipped and exported by TSS?
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Fmoc-Gln(Tmob)-OH is stored at 2-8°C. Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, capable of shipping and exporting this product internationally.
How can I request a sample or quote for Fmoc-Gln(Tmob)-OH?
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To request a sample or a quotation for Fmoc-Gln(Tmob)-OH, please contact the Tech Serve Solutions sales department through our official website or designated contact channels.
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