Fmoc-Dap(Z)-OH

CAS 204316-36-9C26H24N2O6Chemical Synthesis

Fmoc-Dap(Z)-OH (CAS: 204316-36-9), a protected derivative of 2,3-diaminopropionic acid, is a valuable building block in peptide chemistry. With the molecular formula C26H24N2O6 and a molecular weight of 460.48 g/mol, this compound facilitates the incorporation of unnatural amino acids into peptide sequences. It is primarily utilised in chemical synthesis and chemical biology research.

IUPAC: Nα-Fmoc-Nβ-Z-L-2,3-diaminopropionic acid,Fmoc-3-(Z-amino)-L-alanine
Synonyms: Nα-Fmoc-Nβ-Z-L-2,3-diaminopropionic acidFmoc-3-(Z-amino)-L-alanine

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Fmoc-Dap(Z)-OH (C26H24N2O6) — chemical structure, CAS 204316-36-9; Chemistry, fine chemical supplied by Tech Serve Solutions

Chemical BiologyChemical SynthesisDAP (23-Diaminopropionic Acid)Peptide Chemistry

01 /Applications

Peptide Synthesis

This Fmoc-protected amino acid derivative serves as a crucial reagent in solid-phase and solution-phase peptide synthesis. Its protected amino groups allow for controlled stepwise elongation of peptide chains.

Chemical Biology Research

Fmoc-Dap(Z)-OH is employed in the synthesis of modified peptides for studying biological processes. It enables the creation of peptides with specific functionalities or structural alterations for advanced research.

Unnatural Amino Acid Incorporation

As a derivative of an unnatural amino acid, this compound is key for introducing non-proteinogenic residues into peptides. This expands the structural and functional diversity of synthetic peptides.

Chemical Synthesis Intermediate

It acts as an intermediate in complex organic synthesis pathways, where precise control over amino functionalities is required. The orthogonal protection strategy offered by Fmoc and Z groups is advantageous.

02 /Properties

Molecular weight	460.48
Empirical formula	C26H24N2O6
Assay	≥95.0%

03 /Safety & handling

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

204316-36-9

MDL number

MFCD00273467

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is Fmoc-Dap(Z)-OH used for?

Fmoc-Dap(Z)-OH is used in peptide synthesis and chemical biology research as a building block for incorporating protected unnatural amino acids into peptide sequences.

What is the CAS number and formula for Fmoc-Dap(Z)-OH?

The CAS number is 204316-36-9, and the empirical formula (Hill notation) is C26H24N2O6.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies Fmoc-Dap(Z)-OH with an assay of ≥95.0%. This compound is intended for research and development purposes and is not supplied as USP, BP, EP, or pharmaceutical grade.

How should Fmoc-Dap(Z)-OH be handled?

Handle Fmoc-Dap(Z)-OH with appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter may be necessary. It is classified under WGK 2 in Germany, indicating a hazard to water.