Fmoc-Dab(Boc)-OH
Fmoc-Dab(Boc)-OH (CAS 125238-99-5), with the molecular formula C24H28N2O6 and a molecular weight of 440.49, is a protected unnatural amino acid derivative. It serves as a crucial building block in peptide synthesis and chemical biology research. Its structure features orthogonal protecting groups (Fmoc and Boc) that facilitate selective deprotection strategies in complex molecular assembly, making it invaluable for creating modified peptides and peptidomimetics for various scientific investigations.
- IUPAC
- Nα-Fmoc-Nγ-Boc-L-2,4-diaminobutyric acid
Peptide Synthesis
Fmoc-Dab(Boc)-OH is a protected amino acid derivative widely utilized in solid-phase and solution-phase peptide synthesis. The Fmoc group allows for base-labile deprotection, while the Boc group on the side chain amine offers orthogonal protection, enabling controlled peptide chain elongation and the incorporation of modified amino acids.
Chemical Biology
This compound is a key reagent in chemical biology for the construction of peptides with specific functionalities or modified backbones. It aids in the development of peptide-based probes, therapeutic agents, and tools for studying biological processes at a molecular level.
Unnatural Amino Acid Derivatives
As an unnatural amino acid derivative, Fmoc-Dab(Boc)-OH allows for the introduction of novel structural elements into peptides. This can lead to enhanced stability, altered biological activity, or unique binding properties compared to peptides composed solely of natural amino acids.
| Molecular weight | 440.49 |
|---|---|
| Empirical formula | C24H28N2O6 |
| Assay | ≥97.0% (HPLC) |
| Optical activity | [α]20/546 −14.5±1°, c = 1% in methanol |
| Storage temperature | 2-8°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Fmoc-Dab(Boc)-OH used for?
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Fmoc-Dab(Boc)-OH is primarily used as a protected building block in peptide synthesis and chemical biology. Its orthogonal protecting groups facilitate the controlled incorporation of modified amino acids into peptide chains for research and development.
What are the CAS number and molecular formula for Fmoc-Dab(Boc)-OH?
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The CAS number for Fmoc-Dab(Boc)-OH is 125238-99-5, and its molecular formula is C24H28N2O6.
What grade and purity does Tech Serve Solutions supply for Fmoc-Dab(Boc)-OH?
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Tech Serve Solutions supplies Fmoc-Dab(Boc)-OH with an assay of ≥97.0% (HPLC). TSS does not represent this product as USP, BP, or EP grade.
What are the safety and handling recommendations for Fmoc-Dab(Boc)-OH?
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Handling Fmoc-Dab(Boc)-OH requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. The product has a WGK Germany classification of 3, indicating a high hazard.
How is Fmoc-Dab(Boc)-OH stored and shipped?
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Fmoc-Dab(Boc)-OH should be stored at 2-8°C. TSS can export this chemical globally, adhering to all relevant shipping regulations.
How can I request a sample or quote for Fmoc-Dab(Boc)-OH?
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To request a sample or quote for Fmoc-Dab(Boc)-OH, please contact the Tech Serve Solutions sales team through our website or by direct inquiry.
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