Fmoc-Gln(Dod)-OH
Fmoc-Gln(Dod)-OH, CAS 113534-17-1, is a derivative of L-glutamine featuring Nα-Fmoc and Nδ-Dod protecting groups. With a molecular formula of C35H34N2O7 and a molecular weight of 594.65 g/mol, this compound is primarily utilised in peptide synthesis and chemical biology. It serves as a valuable building block for constructing peptides with modified glutamine residues, facilitating research in various biochemical and pharmaceutical applications.
- IUPAC
- Nα-Fmoc-Nδ-(4,4′-dimethoxybenzhydryl)-L-glutamine
Peptide Synthesis
Fmoc-Gln(Dod)-OH is a crucial reagent in solid-phase and solution-phase peptide synthesis. The Fmoc protecting group allows for orthogonal deprotection strategies, while the Dod group protects the side-chain amide of glutamine during coupling reactions.
Chemical Biology Research
This derivative is employed in creating peptides with specific functionalities for studying biological processes. Its use allows for the incorporation of modified glutamine residues into peptides to investigate protein-protein interactions or enzyme mechanisms.
Drug Discovery
As a building block for peptidomimetics and modified peptides, Fmoc-Gln(Dod)-OH finds application in drug discovery programs. It enables the synthesis of novel peptide-based therapeutics with improved stability and bioavailability.
| Molecular weight | 594.65 |
|---|---|
| Empirical formula | C35H34N2O7 |
| Assay | ≥96.0% (HPLC) |
| Storage temperature | 2-8°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Fmoc-Gln(Dod)-OH used for?
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Fmoc-Gln(Dod)-OH is primarily used as a protected amino acid derivative in peptide synthesis and chemical biology research. It facilitates the incorporation of modified glutamine residues into peptide sequences.
What are the CAS number and formula for Fmoc-Gln(Dod)-OH?
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The CAS number for Fmoc-Gln(Dod)-OH is 113534-17-1, and its empirical formula (Hill notation) is C35H34N2O7.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Fmoc-Gln(Dod)-OH with an assay of ≥96.0% (HPLC). We do not represent this product as USP, BP, EP, or pharmacopoeia grade.
How should Fmoc-Gln(Dod)-OH be handled and stored?
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Handling requires appropriate personal protective equipment, including eyeshields, gloves, and a P1 (EN143) or N95 (US) respirator filter. Store the compound at 2-8°C.
Is Fmoc-Gln(Dod)-OH a controlled substance?
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Based on the provided data, Fmoc-Gln(Dod)-OH is not classified as a controlled substance.
How are products like Fmoc-Gln(Dod)-OH packed, shipped, and exported?
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Tech Serve Solutions packs, ships, and exports fine chemicals with careful consideration for product integrity and regulatory compliance. Specific packaging details will be provided upon order confirmation.
How can I request a sample or quote for Fmoc-Gln(Dod)-OH?
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To request a sample or quote for Fmoc-Gln(Dod)-OH, please contact our sales team through the website or by phone. Please reference the product name and CAS number.
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