Fmoc-GABA-OH
Fmoc-GABA-OH (CAS: 116821-47-7, C19H19NO4) is a derivative of gamma-aminobutyric acid (GABA), a non-proteinogenic amino acid. It features the Fmoc (9-fluorenylmethyloxycarbonyl) protecting group, commonly used in solid-phase peptide synthesis. This compound serves as a valuable building block in chemical biology and synthesis, particularly for introducing GABA or related structural motifs into peptides and other complex molecules.
- IUPAC
- 4-(Fmoc-amino)butyric acid,Fmoc-GABA
- Synonyms
- 4-(Fmoc-amino)butyric acidFmoc-GABA
Peptide Synthesis
Fmoc-GABA-OH is utilised as a protected amino acid building block in solid-phase peptide synthesis (SPPS). Its Fmoc group allows for orthogonal deprotection strategies, facilitating the controlled assembly of peptide chains.
Chemical Biology Research
This compound aids in the development of modified peptides and peptidomimetics. It enables researchers to study the biological roles of GABAergic systems or to create novel molecules with specific pharmacological properties.
Drug Discovery and Development
Fmoc-GABA-OH can be incorporated into potential drug candidates. Its structure allows for the exploration of new therapeutic agents targeting neurological pathways or other biological processes influenced by GABA.
Organic Synthesis
Beyond peptide chemistry, this compound serves as a versatile intermediate in various organic synthesis pathways. It can be used to introduce a protected GABA moiety into diverse organic structures.
| Molecular weight | 325.36 |
|---|---|
| Empirical formula | C19H19NO4 |
| Assay | ≥97.0% (HPLC) |
| Storage temperature | 2-8°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Fmoc-GABA-OH used for?
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Fmoc-GABA-OH is primarily used as a protected amino acid building block in solid-phase peptide synthesis, in chemical biology research, drug discovery, and general organic synthesis to introduce a protected gamma-aminobutyric acid moiety.
What are the CAS number and molecular formula for Fmoc-GABA-OH?
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The CAS number is 116821-47-7, and the molecular formula is C19H19NO4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Fmoc-GABA-OH with an assay of ≥97.0% (HPLC). This product is typically supplied for research and laboratory use and is not represented as USP, BP, EP, or pharmacopoeia grade.
How should Fmoc-GABA-OH be handled and stored?
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Handle Fmoc-GABA-OH with appropriate personal protective equipment, including eyeshields and gloves. A respirator filter like type N95 (US) or type P1 (EN143) may be necessary. Store the chemical at 2-8°C to maintain its integrity.
Is Fmoc-GABA-OH a controlled substance?
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The provided safety data does not indicate that Fmoc-GABA-OH is a controlled or scheduled substance.
How is this chemical shipped and exported?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, capable of handling international shipments according to relevant regulations.
How can I request a quote or sample of Fmoc-GABA-OH?
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Please contact the Tech Serve Solutions sales team through our website or direct contact details to request a quote or inquire about sample availability.
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