4-Methyl-3-thienylboronic acid
4-Methyl-3-thienylboronic acid (CAS: 177735-11-4) is a heterocyclic organoboron compound with the molecular formula C5H7BO2S and a molecular weight of 141.98 g/mol. This boronic acid derivative serves as a key building block in organic synthesis, particularly for the construction of complex molecules. Its applications span the development of biologically active compounds and advanced materials through cross-coupling reactions and other synthetic methodologies.
- IUPAC
- (4-Methylthien-3-yl)boronic acid,(4-Methylthiophen-3-yl)boronic acid,(4-Methylthiophen-3-yl)dihydroxyborane,4-Methyl-3-thiopheneboronic acid
- Synonyms
- (4-Methylthien-3-yl)boronic acid(4-Methylthiophen-3-yl)boronic acid(4-Methylthiophen-3-yl)dihydroxyborane4-Methyl-3-thiopheneboronic acid
Synthesis of Biologically Active Molecules
Utilised as a reactant in the preparation of selective sphingosine phosphate receptor antagonists and biarylimidazole derivatives with potential H+/K+ ATPase inhibitory activity. It also features in the synthesis of benzothienopyrimidinones, which are investigated as inhibitors of human protooncogene proviral insertion site in Moloney murine leukemia virus kinases.
Advanced Materials Synthesis
Employed in the synthesis of arene-functionalised fullerenes through rhodium-catalyzed hydroarylation, contributing to the development of novel carbon-based materials.
Suzuki Cross-Coupling Reactions
A versatile reagent for Suzuki cross-coupling reactions, enabling the formation of carbon-carbon bonds and the construction of complex organic structures.
| Molecular weight | 141.98 |
|---|---|
| Empirical formula | C5H7BO2S |
| Assay | ≥95% |
| Storage temperature | 2-8°C |
| Application | Reactant for preparation of biologically active molecules:• Selective sphingosine phosphate receptor antagonists1• Biarylimidazole derivatives as H+/K+ ATPase inhibitors2• Benzothienopyrimidinones as inhibitors of human protooncogene proviral insertion site in moloney murine leukemia virus kinases3Used in:• Synthesis of arene-functionalized fullerenes via rhodium-catalyzed hydroarylation4• Suzuki cross-coupling reactions5 |
| Melting point | 138-144 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Methyl-3-thienylboronic acid used for?
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4-Methyl-3-thienylboronic acid is used as a reactant in the synthesis of biologically active molecules, including selective sphingosine phosphate receptor antagonists and H+/K+ ATPase inhibitors. It is also used in the synthesis of arene-functionalised fullerenes and in Suzuki cross-coupling reactions.
What are the CAS number and chemical formula for 4-Methyl-3-thienylboronic acid?
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The CAS number is 177735-11-4 and the chemical formula is C5H7BO2S.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Methyl-3-thienylboronic acid with a purity of ≥95%. This product is not supplied in USP, BP, or EP grade.
How should 4-Methyl-3-thienylboronic acid be handled and stored?
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Handling requires personal protective equipment including eyeshields, gloves, and a type N95 (US) or type P1 (EN143) respirator filter. It should be stored at 2-8°C.
How is 4-Methyl-3-thienylboronic acid packed, shipped, and exported?
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4-Methyl-3-thienylboronic acid is carefully packed to ensure stability during transport and is available for global export by Tech Serve Solutions.
How can I request a sample or quote for 4-Methyl-3-thienylboronic acid?
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To request a sample or a quote, please contact the Tech Serve Solutions sales team via our website or direct inquiry.
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