Pentyllithium solution
Pentyllithium solution (CAS 3525-31-3, CH3(CH2)3CH2Li) is a highly reactive organolithium reagent supplied by Tech Serve Solutions. With a molecular weight of 78.08 g/mol, this compound is primarily used in organic synthesis for introducing the pentyl group. It is supplied as a solution in heptane, typically at a 2.2 M concentration. Its reactivity demands careful handling under inert conditions.
- IUPAC
- Amyllithium
- Synonyms
- Amyllithium
Alkylations
Pentyllithium serves as a strong nucleophile in organic synthesis, enabling the alkylation of various electrophiles. This is crucial for forming carbon-carbon bonds in the construction of complex organic molecules.
Organometallic Synthesis
As an organolithium compound, it is a key reagent in the formation of other organometallic species and is used in transformations where a potent, non-polar organometallic reagent is required.
Deprotonation Reactions
Its strong basicity allows pentyllithium to be used as a base for deprotonating weakly acidic C-H bonds, facilitating subsequent reactions at the deprotonated site.
| Molecular weight | 78.08 |
|---|---|
| Linear formula | CH3(CH2)3CH2Li |
| Density | 0.708 g/mL at 25 °C |
| Concentration | 2.2 M in heptane25 % (w/w) |
Hazard statements
- H225Highly flammable liquid and vapour
- H304May be fatal if swallowed and enters airways
- H314Causes severe skin burns and eye damage
- H340May cause genetic defects
- H350May cause cancer
Precautionary statements
- P201Obtain special instructions before use
- P210Keep away from heat, sparks and open flames. No smoking
- P280Wear protective gloves, clothing and eye/face protection
- P301IF SWALLOWED
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Transport (UN / ADR) | UN 3394 4.2/PG 1 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,T |
| Risk statements (R) | 45-46-11-14-17-35-65 |
| Safety statements (S) | 53-16-26-36/37/39-45-62 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Pentyllithium solution used for?
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Pentyllithium solution is used in organic synthesis for alkylation reactions, the formation of other organometallic reagents, and as a strong base for deprotonation of acidic C-H bonds.
What is the CAS number and chemical formula for Pentyllithium solution?
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The CAS number is 3525-31-3 and the chemical formula is CH3(CH2)3CH2Li.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Pentyllithium solution at 2.2 M in heptane (25% w/w). We do not represent this product as USP, BP, or EP grade. For specific assay details, please refer to the product's Certificate of Analysis.
How should Pentyllithium solution be handled safely?
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Pentyllithium solution is a highly flammable liquid and vapour, causes severe skin burns and eye damage, and may cause genetic defects and cancer. It is also dangerous if swallowed and may cause lung damage. Handle with extreme caution under an inert atmosphere, wearing appropriate personal protective equipment including gloves, goggles, and respiratory protection.
How is Pentyllithium solution shipped and exported?
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Pentyllithium solution is classified as UN 3394, Hazard Class 4.2 (Spontaneously combustible) with Packing Group I. Tech Serve Solutions adheres to all international regulations for the safe packaging, shipping, and export of hazardous chemicals.
How can I request a sample or quote for Pentyllithium solution?
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To request a sample or a quote for Pentyllithium solution, please contact our sales team through the website or by phone. Provide your required quantity and shipping details.
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