Boc-D-Phe(2-Cl)-OH
Boc-D-Phe(2-Cl)-OH (CAS: 80102-23-4) is a chiral unnatural amino acid derivative. With a molecular weight of 299.75 g/mol and empirical formula C14H18ClNO4, this compound features a protected D-phenylalanine core substituted with chlorine at the ortho position. It serves as a valuable building block in chemical synthesis and peptide chemistry, particularly for creating modified peptides and complex organic molecules.
- IUPAC
- Boc-2-chloro-D-phenylalanine

Peptide Synthesis
Utilised as a non-natural amino acid building block for the incorporation of modified phenylalanine residues into peptide chains, enabling the development of novel peptidomimetics and therapeutic agents.
Chemical Synthesis
Serves as a key intermediate in the synthesis of complex organic molecules and pharmaceuticals where precise stereochemistry and specific functionalization are required.
Chemical Biology Research
Employed in research to investigate structure-activity relationships in biologically relevant molecules and to probe protein function through the introduction of unnatural amino acids.
| Molecular weight | 299.75 |
|---|---|
| Empirical formula | C14H18ClNO4 |
| Assay | ≥98.0% (TLC) |
| Optical activity | [α]20/D +23.5±2°, c = 1% in ethyl acetate |
| Melting point | 94-98 °C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Boc-D-Phe(2-Cl)-OH used for?
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Boc-D-Phe(2-Cl)-OH is primarily used as a building block in peptide synthesis and for the construction of complex organic molecules in chemical synthesis and chemical biology research.
What is the CAS number and formula for Boc-D-Phe(2-Cl)-OH?
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The CAS number is 80102-23-4 and the empirical formula is C14H18ClNO4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Boc-D-Phe(2-Cl)-OH with an assay of ≥98.0% (TLC). We do not represent this product as USP, BP, or EP grade.
How should Boc-D-Phe(2-Cl)-OH be handled safely?
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Handling requires appropriate personal protective equipment including eyeshields and gloves. Use a type N95 (US) or type P1 (EN143) respirator filter. This compound has a WGK rating of 3.
How is this chemical shipped and exported?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, adhering to all necessary regulations for safe and compliant international shipping.
How can I request a sample or quote for Boc-D-Phe(2-Cl)-OH?
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Please contact our sales team through the website to request a sample or a quotation for Boc-D-Phe(2-Cl)-OH.
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