Boc-D-Phe(2-CN)-OH
Boc-D-Phe(2-CN)-OH (CAS 261380-28-3), with the molecular formula C15H18N2O4 and a molecular weight of 290.31 g/mol, is a protected unnatural amino acid derivative. It is utilised in chemical biology and synthesis, particularly within peptide chemistry. This compound serves as a valuable building block for creating complex peptides and peptidomimetics with modified structures for research purposes.
- IUPAC
- Boc-2-cyano-D-phenylalanine
- Synonyms
- Boc-2-cyano-D-phenylalanine

Peptide Synthesis
Boc-D-Phe(2-CN)-OH is employed as a non-canonical amino acid building block in solid-phase or solution-phase peptide synthesis. Its unique cyano-substituted phenylalanine structure allows for the introduction of specific modifications into peptide chains.
Chemical Biology Research
This compound facilitates the study of peptide structure-activity relationships and protein-ligand interactions. Its incorporation into biomolecules can modulate their biological properties and enhance their utility as research tools.
Drug Discovery and Development
As a specialised intermediate, Boc-D-Phe(2-CN)-OH can be used in the synthesis of novel pharmaceutical candidates. The unnatural amino acid moiety may confer enhanced metabolic stability or altered receptor binding profiles.
| Molecular weight | 290.31 |
|---|---|
| Empirical formula | C15H18N2O4 |
| Assay | ≥98.0% (HPLC) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Boc-D-Phe(2-CN)-OH used for?
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Boc-D-Phe(2-CN)-OH is primarily used in chemical synthesis, particularly for peptide chemistry and chemical biology research. It serves as a building block for unnatural amino acid derivatives and modified peptides.
What are the CAS number and chemical formula of Boc-D-Phe(2-CN)-OH?
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The CAS number for Boc-D-Phe(2-CN)-OH is 261380-28-3, and its chemical formula is C15H18N2O4.
What grade and purity does Tech Serve Solutions supply for Boc-D-Phe(2-CN)-OH?
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Tech Serve Solutions supplies Boc-D-Phe(2-CN)-OH with an assay of ≥98.0% (HPLC). This product is intended for research and laboratory use; TSS does not represent it as USP, BP, EP, or other pharmacopoeia grades.
How should Boc-D-Phe(2-CN)-OH be handled safely?
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When handling Boc-D-Phe(2-CN)-OH, it is essential to wear appropriate personal protective equipment, including eyeshields and gloves. A respirator filter, such as type N95 (US) or type P1 (EN143), is recommended. The compound has a WGK Germany rating of 3, indicating a high hazard to water.
Is Boc-D-Phe(2-CN)-OH available for export?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including Boc-D-Phe(2-CN)-OH, and can cater to international orders.
How can I request a quote or sample for Boc-D-Phe(2-CN)-OH?
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To request a quote or a sample of Boc-D-Phe(2-CN)-OH, please contact our sales team through the designated channels on the Tech Serve Solutions website.
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