Boc-D-Phe(2-F)-OH

CAS 114873-10-8C14H18FNO4Chemical Synthesis

Boc-D-Phe(2-F)-OH (CAS 114873-10-8) is a fluorinated unnatural amino acid derivative with the molecular formula C14H18FNO4 and a molecular weight of 283.30 g/mol. This protected amino acid is a valuable building block in chemical synthesis, particularly within peptide chemistry and chemical biology. Its unique structure, featuring a fluorine atom on the phenyl ring, allows for the exploration of novel peptide modifications and drug discovery.

IUPAC: Boc-2-fluoro-D-phenylalanine
Synonyms: Boc-2-fluoro-D-phenylalanine

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Boc-D-Phe(2-F)-OH (C14H18FNO4) — chemical structure, CAS 114873-10-8; Chemistry, fine chemical supplied by Tech Serve Solutions

Chemical BiologyChemical SynthesisPeptide ChemistryPhenylalanine Derivatives

01 /Applications

Peptide Synthesis

Utilised as a building block in solid-phase or solution-phase peptide synthesis to incorporate unnatural amino acid residues. The fluorine substitution can influence peptide conformation, stability, and binding interactions.

Chemical Biology Research

Employed in the design and synthesis of modified peptides or peptidomimetics for studying biological processes, enzyme inhibition, or receptor interactions.

Drug Discovery and Development

Serves as a key intermediate in the synthesis of novel therapeutic agents where fluorinated amino acids are required to enhance pharmacokinetic or pharmacodynamic properties.

Organic Synthesis

A versatile reagent in organic synthesis for constructing complex molecules containing fluorinated phenylalanine motifs.

02 /Properties

Molecular weight	283.30
Empirical formula	C14H18FNO4
Assay	≥98.0% (TLC)
Optical activity	[α]20/D −10±1°, c = 1% in ethyl acetate
Melting point	94-98 °C

03 /Safety & handling

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

114873-10-8

MDL number

MFCD00672521

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is Boc-D-Phe(2-F)-OH used for?

Boc-D-Phe(2-F)-OH is primarily used as a building block in chemical synthesis, particularly for peptide chemistry, chemical biology research, and drug discovery, enabling the incorporation of fluorinated unnatural amino acid residues.

What is the CAS number and molecular formula for Boc-D-Phe(2-F)-OH?

The CAS number is 114873-10-8 and the molecular formula is C14H18FNO4.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies Boc-D-Phe(2-F)-OH with an assay of ≥98.0% (TLC). This product is intended for research and laboratory use; TSS does not represent it as USP, BP, or EP grade.

How should Boc-D-Phe(2-F)-OH be handled safely?

Appropriate personal protective equipment, including eyeshields, gloves, and a type N95 (US) or type P1 (EN143) respirator filter, should be used when handling this compound. Refer to the safety data sheet for comprehensive handling information.

Does TSS export Boc-D-Phe(2-F)-OH?

Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including Boc-D-Phe(2-F)-OH, and can ship to numerous international destinations.