Boc-D-Phe(2,4-Cl2)-OH
Boc-D-Phe(2,4-Cl2)-OH (CAS: 114873-12-0) is a protected unnatural amino acid derivative with the molecular formula C14H17Cl2NO4. This compound serves as a valuable building block in chemical synthesis, particularly within peptide chemistry and chemical biology research. Its structure, featuring a Boc-protected D-phenylalanine core with dichloro substitutions, allows for specific incorporation into complex molecular architectures. Tech Serve Solutions offers this reagent for research and development purposes.
- IUPAC
- Boc-2,4-dichloro-D-phenylalanine
- Synonyms
- Boc-2,4-dichloro-D-phenylalanineN-Boc-2,4-dichloro-D-phenylalanine
Peptide Synthesis
Boc-D-Phe(2,4-Cl2)-OH is utilised as a non-canonical amino acid precursor in solid-phase or solution-phase peptide synthesis. It enables the creation of peptides with modified side chains, potentially influencing their biological activity or structural properties.
Chemical Biology Research
This compound can be incorporated into biologically active molecules or probes. Its unique structural features, including the halogenated phenyl ring, may confer specific binding affinities or metabolic stability for investigational purposes.
Organic Synthesis Intermediate
As a chiral building block, Boc-D-Phe(2,4-Cl2)-OH is employed in the synthesis of complex organic molecules beyond peptides. Its functional groups allow for further chemical transformations and elaborations.
| Molecular weight | 334.20 |
|---|---|
| Empirical formula | C14H17Cl2NO4 |
| Assay | ≥98.0% (TLC) |
| Optical activity | [α]20/D +32.5±1°, c = 1% in methanol |
| Melting point | 133-137 °C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Boc-D-Phe(2,4-Cl2)-OH used for?
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Boc-D-Phe(2,4-Cl2)-OH is primarily used as a building block in peptide synthesis, chemical biology research, and as an intermediate in organic synthesis, particularly for creating molecules with unnatural amino acid residues.
What is the CAS number and formula for Boc-D-Phe(2,4-Cl2)-OH?
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The CAS number is 114873-12-0, and the empirical formula is C14H17Cl2NO4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Boc-D-Phe(2,4-Cl2)-OH with an assay of ≥98.0% (TLC). This product is intended for research purposes and is not supplied as USP, BP, EP, or pharmacopoeia grade.
How should Boc-D-Phe(2,4-Cl2)-OH be handled safely?
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Handle with appropriate personal protective equipment, including eyeshields and gloves. Use a type N95 (US) or type P1 (EN143) respirator filter if airborne exposure is possible. Refer to the safety data sheet for comprehensive handling instructions.
Is this compound suitable for pharmaceutical manufacturing?
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This product is supplied for research and development purposes. Tech Serve Solutions does not represent it as suitable for direct pharmaceutical manufacturing or clinical use without further qualification.
How can I request a quote or sample?
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To request a quote or sample, please contact our sales team through the website or provide your requirements via the dedicated inquiry form.
How is Boc-D-Phe(2,4-Cl2)-OH shipped?
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Boc-D-Phe(2,4-Cl2)-OH is carefully packed and exported in compliance with international shipping regulations for chemical substances.
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